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Strain Registration

Strain: LE-Dyrk1aem3Mcwi

Symbol: LE-Dyrk1aem3Mcwi
Strain: LE-Dyrk1aem3
Substrain: Mcwi
RGD ID: 25394526
Citation ID: RRID:RGD_25394526
Ontology ID: RS:0004780
Type: mutant
Source: Generated with support from the Simons Foundation Autism Research Initiative (SFARI); MCW Gene Editing Rat Resource Center; Contact MCW rat distribution at mcwcustomrats@mcw.edu
Origin: The rat strain was produced by injecting CRISPR/Cas9 targeting rat Dyrk1a into Crl:LE embryos. The result is a 5-bp deletion in exon 3 of the gene.
Last Known Status: Unknown
Research Usage Developmental delay, Intellectual disability, Epilepsy (from SFARI GENE)
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