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Strain Registration

Strain: LE-Nrxn1em1Mcwi

Symbol: LE-Nrxn1em1Mcwi
Strain: LE-Nrxn1em1
Substrain: cwi
RGD ID: 25330089
Citation ID: RRID:RGD_25330089
Ontology ID: RS:0004783
Type: mutant
Source: Generated with support from the Simons Foundation Autism Research Initiative (SFARI ); MCW Gene Editing Rat Resource Center; Contact MCW rat distribution at mcwcustomrats@mcw.edu
Origin: The rat strain was produced by injecting CRISPR/Cas9 targeting rat Nrxn1 into Crl:LE embryos. The result is a 4-bp deletion in exon 1.
Last Known Status: Unknown
Research Usage Autism, ADHD, Developmental delay, Intellectual disability, Epilepsy, Schizophrenia, Bipolar disorder (from SFARI GENE)
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