Strain Report - Rat Genome Database

Name: LE- Cntnap2 em1Mcwi
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain Registration

General

Strain: LE-Cntnap2^em1Mcwi

Symbol:

LE-Cntnap2^em1Mcwi

Strain:

LE-Cntnap2^em1

Substrain:

Mcwi

RGD ID:

25330087

Citation ID:

RRID:RGD_25330087

Ontology ID:

RS:0004782

Alleles:

Cntnap2^em1Mcwi

Type:

mutant

Source:

Generated with support from the Simons Foundation Autism Research Initiative (SFARI); MCW Gene Editing Rat Resource Center; Contact MCW rat distribution at mcwcustomrats@mcw.edu

Origin:

The rat strain was produced by injecting CRISPR/Cas9 targeting rat Cntnap2 into Crl:LE embryos. The result is a 1-bp deletion in exon 6 of the gene.

Last Known Status:

Unknown

Research Usage

Autism, ADHD, Developmental delay, Intellectual disability, Epilepsy, Bipolar disorder (from SFARI GENE)

Genotyping Protocol

Download Genotyping Protocol

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	4	75,691,075 - 75,691,075	RGD_MAPPER_PIPELINE	Rnor6.0

Annotation Click to see Annotation Detail View

References

Region

Allelic Variants

Name	Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Assembly
Cntnap2em1Mcwi-var1	chr4	75691075	75691075	C	-	deletion	Rnor_6.0

Additional Information

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: LE-Cntnap2em1Mcwi

Strain: LE-Cntnap2^em1Mcwi