Strain Report - Rat Genome Database

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Strain: WKY.LEW-(D13Arb10-D13Arb15)(D16Rat88-D16Rat40)/Tja

Symbol: WKY.LEW-(D13Arb10-D13Arb15)(D16Rat88-D16Rat40)/Tja
Strain: WKY.LEW-(D13Arb10-D13Arb15)(D16Rat88-D16Rat40)/Tja
RGD ID: 2325774
Citation ID: RRID:RRRC_00707
Ontology ID: RS:0002415
Also Known As: WKY.LCrgn1,2; WKY.LEW-(D13Arb10-D13Arb15)(D16Rat88-D16Rat40); WKY.LEW-(D13Arb10-D13Arb15)(D16Rat88-D16Rat40)/Tja
Type: congenic
Available Source: Rat Resource and Research Center
Origination: Imperial College, London, UK
Description: WKY.LEW-(D13Arb10-D13Arb15) were crossed with WKY.LEW-(D16Rat88-D16Rat40), the F1 were backcrossed to WKY.LEW-(D13Arb10-D13Arb15) and then the offsprings were intercrossed
Last Known Status: Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-01-26)





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Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Genetic Loci Modulate Macrophage Activity and Glomerular Damage in Experimental Glomerulonephritis. Behmoaras J, etal., J Am Soc Nephrol. 2010 May 20.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other These have direct additive effect of both the QTLs Glom15 and Glom16 2325762
strain_phys_biochem These have reduced macrophage infiltration, few glomerular crescents and decreased expression of TNF-alpha 2325762

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-02-12 WKY.LEW-(D13Arb10-D13Arb15)(D16Rat88-D16Rat40)/Tja    WKY.LEW-(D13Arb10-D13Arb15)(D16Rat88-D16Rat40   Symbol updated 68687 APPROVED
2013-02-12 WKY.LEW-(D13Arb10-D13Arb15)(D16Rat88-D16Rat40)/Tja    WKY.LEW-(D13Arb10-D13Arb15)(D16Rat88-D16Rat40   Name updated 68913 APPROVED
2013-02-12 WKY.LEW-(D13Arb10-D13Arb15)(D16Rat88-D16Rat40)/Tja    WKY.LEW-(D13Arb10-D13Arb15)(D16Rat88-D16Rat40   Symbol updated 68687 APPROVED
2013-02-12 WKY.LEW-(D13Arb10-D13Arb15)(D16Rat88-D16Rat40)/Tja    WKY.LEW-(D13Arb10-D13Arb15)(D16Rat88-D16Rat40   Name updated 68913 APPROVED

Database Acc Id Source(s)
RRRC RRRC:00707 RGD