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Strain Registration

Strain: SHR.BN-(D3Rat159-D3Rat1)(D6Rat40-D6Rat170)/Mco

Symbol: SHR.BN-(D3Rat159-D3Rat1)(D6Rat40-D6Rat170)/Mco
Strain: SHR.BN-(D3Rat159-D3Rat1)(D6Rat40-D6Rat170)
Substrain: Mco
RGD ID: 2316928
Citation ID: RRID:RGD_2316928
Ontology ID: RS:0002378
Also Known As: SHR.BN-(D3Rat159-D3Rat1)(D6Rat40-D6Rat170)/Mco; SHR.BN (3+6)
Type: congenic
Available Source: Not Available
Origination: Medical College of Ohio, Toledo, Ohio, USA
Description: this double congenic strain is bred by crossing female SHR.BN-(D6Rat40-D6Rat170)/Mco with male SHR.BN-(D3Rat159-D3Rat1)/Mco and selecting heterozygous animals in the F1 progeny; these were then mated to fix the BN allele
Last Known Status: Unknown





Disease Annotations     Click to see Annotation Detail View
Hyperplasia  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Neointimal hyperplasia and vasoreactivity are controlled by genetic elements on rat chromosome 3. Nestor Kalinoski AL, etal., Hypertension. 2010 Feb;55(2):555-61. Epub 2009 Dec 21.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease less than additive effect was seen, suggesting that the net effect of these allele do not account for the hyperplasia observed in F2 progeny 2316923

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-03-02 SHR.BN-(D3Rat159-D3Rat1)(D6Rat40-D6Rat170)/Mco    SHR.BN-(D3Rat159-D3Rat1)(D6Rat40-D6Rat170)/Mco    Name updated 68913 APPROVED
2010-03-02 SHR.BN-(D3Rat159-D3Rat1)(D6Rat40-D6Rat170)/Mco    SHR.BN-(D3Rat159-D3Rat1)(D6Rat40-D6Rat170)/Mco    Name updated 68913 APPROVED
2010-03-02 SHR.BN-(D3Rat159-D3Rat1)(D6Rat40-D6Rat170)/Mco    SHR.BN-(D3Rat159-D3Rat1)(D6Rat40-D6Rat170)/Mco    Name updated 68913 APPROVED