Strain Report - Rat Genome Database

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Strain: KFRS3B/Kyo

Symbol: KFRS3B/Kyo
Strain: KFRS3B
Substrain: Kyo
RGD ID: 2314377
RRID: RGD_2314377
Ontology ID: RS:0002033
Also known as: SRR03-grey;Pearl;NBRP Rat No: 0571
Type: mutant
Source: National BioResource Project for the Rat in Japan
Origin: A male rat "SRR-Rocket Science" was introduced from American fancy rat colony (Spoiled Ratten Rattery: SRR, in Kansas City, Missouri) to Kyoto University on July 13, 2005. Inbreeding started from F1 progeny of male "SRR-Rocket Science" and a female PVG/Seac. Homozygous rats for grey mutation were selected for inbreeding.
Inbred Generations: F17
Last Known Status: Cryopreserved Sperm
Research Usage Ophthalmology; Dermatology






Phenotype Values via PhenoMiner     Click to see Annotation Detail View
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Clinical Measurement
heart rate
systolic blood pressure
body weight
body temperature
red blood cell count
blood hemoglobin level
white blood cell count
platelet count
hematocrit
mean corpuscular volume
plasma glucose level
plasma aspartate aminotransferase activity level
plasma alanine aminotransferase activity level
plasma alkaline phosphatase activity level
plasma total protein level
plasma albumin level
plasma phosphate level
plasma chloride level
plasma sodium level
plasma potassium level
heart wet weight
heart weight to body weight ratio
both kidneys wet weight
lung wet weight
urine potassium level
urine sodium level
brain weight to body weight ratio
both kidneys wet weight as percentage of body weight
liver weight as percentage of body weight
spleen weight to body weight ratio
brain wet weight
lung weight to body weight ratio
liver wet weight
both adrenal glands wet weight
spleen wet weight
both testes wet weight
timed urine volume
mean corpuscular hemoglobin level
mean corpuscular hemoglobin concentration
blood basophil count to total leukocyte count ratio
blood eosinophil count to total leukocyte count ratio
blood lymphocyte count to total leukocyte count ratio
blood monocyte count to total leukocyte count ratio
total plasma calcium level
urine chloride level
plasma creatinine level
plasma triglyceride level
plasma total cholesterol level
plasma urea nitrogen level
both adrenal glands weight to body weight ratio
plasma high density lipoprotein cholesterol level
plasma low density lipoprotein cholesterol level
both testes wet weight to body weight ratio
urine sodium excretion rate to body weight ratio
timed urine volume to body weight ratio
urine chloride excretion rate to body weight ratio
urine potassium excretion rate to body weight ratio
total plasma bilirubin level
blood segmented neutrophil count to total leukocyte count ratio
blood band neutrophil count to total leukocyte count ratio
non-specified leukocyte count to total leukocyte count ratio
plasma albumin to plasma total protein ratio

References

References - curated
1. Personal Communication with NBRP
2. RGD Automated Pipelines

Region

Damaging Variants
Number of Damaging Variants
SampleRnor_6.0Rnor_5.0RGSC_v3.4
KFRS3B/Kyo (KyushuU) 1243


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Grey mutation (light grey hair color) and Pearl mutation (hair color dilution and homozygous lethal). 1302502
strain_reproduction Maintained by crossing of heterozygous and wild-type for Pearl mutation. This strain is heterozygous for Pearl (segregating strain) and homozygous for grey. Good breeding performance. 1302502

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-05-29 KFRS3B/Kyo    KFRS3B/Kyo    Name updated 68913 APPROVED
2012-05-29 KFRS3B/Kyo    KFRS3B/Kyo    Name updated 68913 APPROVED