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Strain: F344-Tg(Cyp1a1-Ren2)10.LEW-(D10Rat142-D10Rat15)/Jmul

Symbol: F344-Tg(Cyp1a1-Ren2)10.LEW-(D10Rat142-D10Rat15)/Jmul
Strain: F344-Tg(Cyp1a1-Ren2)10.LEW-(D10Rat142-D10Rat15)
Substrain: Jmul
RGD ID: 2313922
Citation ID: RRID:RGD_2313922
Ontology ID: RS:0001932
Previously known as: Ren2.F-MOD-L;F344.LEW-(D10Rat142-D10Rat15)/Jmul; F344-Tg(Cyp1a1-Ren2)10.LEW-(D10Rat142-D10Rat15)/Jmul
Type: congenic
Source: Molecular Physiology Lab, CVS, QMRI, University of Edinburgh, Edinburgh, UK
Origin: F344-Tg(Cyp1a1-Ren2)10Jmul (also named Ren2.F) males (carrying the transgene Ren2 on chr Y) and Lewis females were bred to produce F1 rats.F1 males were backcrossed to F344 females to produce BC-F344. After 12 backcross nerations, males and females heterozygous for F344/Lew in the reduced MOD QTLregion were brother-sister mated to generate aimals that were homozygous Lew/Lew for the MOD QTL region but homozygous F344/F344 for the rest of the genome.
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21088,207,600 - 92,238,497RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01091,345,679 - 95,508,221RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01091,113,514 - 95,243,104RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41092,448,353 - 96,667,338RGD_MAPPER_PIPELINERGSC3.4

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype


References - curated
1. Liu X, etal., J Biol Chem. 2009 Jun 5;284(23):15564-72. Epub 2009 Mar 23.
2. RGD Automated Pipelines


Position Markers

Flank 1 / 1 (D10Rat142)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21088,207,600 - 88,207,815 (+)MAPPER
Rnor_6.01091,345,679 - 91,345,893NCBI
Rnor_5.01091,113,514 - 91,113,728UniSTS
RGSC_v3.41092,448,354 - 92,448,568UniSTS
RGSC_v3.41092,448,353 - 92,448,568RGD
RGSC_v3.11092,462,723 - 92,462,938RGD
Celera1086,908,452 - 86,908,666UniSTS
RH 3.4 Map10899.0RGD
RH 3.4 Map10899.0UniSTS
SHRSP x BN Map1066.5RGD
SHRSP x BN Map1066.5UniSTS
Cytogenetic Map10q32.1UniSTS

Flank 2 / 1 (D10Rat15)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21092,238,327 - 92,238,497 (+)MAPPER
Rnor_6.01095,508,052 - 95,508,221NCBI
Rnor_5.01095,242,935 - 95,243,104UniSTS
RGSC_v3.41096,666,931 - 96,667,338RGD
RGSC_v3.41096,667,046 - 96,667,215UniSTS
RGSC_v3.11096,681,301 - 96,681,708RGD
Celera1090,903,901 - 90,904,070UniSTS
RH 3.4 Map101039.2RGD
RH 3.4 Map101039.2UniSTS
RH 2.0 Map101122.9RGD
SHRSP x BN Map1073.35RGD
FHH x ACI Map1076.9099RGD
Cytogenetic Map10q32.1UniSTS

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other This congenic strain contains reduced Bp342 QTL (~4.0 Mb Lewis region on F344 background) 2313695

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-30 F344-Tg(Cyp1a1-Ren2)10.LEW-(D10Rat142-D10Rat15)/Jmul    F344.LEW-(D10Rat142-D10Rat15)/Jmul    Symbol updated 68687 APPROVED
2017-03-30 F344-Tg(Cyp1a1-Ren2)10.LEW-(D10Rat142-D10Rat15)/Jmul    F344.LEW-(D10Rat142-D10Rat15)/Jmul    Symbol updated 68687 APPROVED