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Strain Registration

Strain: SD-Tg(Ins2-IAPP)Soel

Symbol: SD-Tg(Ins2-IAPP)Soel
Strain: SD-Tg(Ins2-IAPP)
Substrain: Soel
RGD ID: 2313588
Citation ID: RRID:RGD_2313588
Ontology ID: RS:0002125
Previously known as: human IAPP rat;HIP rat; line 9
Type: transgenic
Source: Pfizer, Inc, Groton, Connecticut
Origin: Crl:SD rats were microinjected with cDNA encompassing the human IAPP was fused with rat insulin II promoter
Last Known Status: Unknown





Disease Annotations     Click to see Annotation Detail View

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References

References - curated
# Reference Title Reference Citation
1. Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes. Butler AE, etal., Diabetes. 2004 Jun;53(6):1509-16.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease Develop diabetes between 5-10 months of age 2313576