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Strain Registration

Strain: SHR.BN-(D10Mgh3-Srebf1)/Ipcv

Symbol: SHR.BN-(D10Mgh3-Srebf1)/Ipcv
Strain: SHR.BN-(D10Mgh3-Srebf1)
Substrain: Ipcv
RGD ID: 2300217
Citation ID: RRID:RGD_2300217
Ontology ID: RS:0001637
Previously known as: SHR.BN-D10Mgh3/Srebf1;SHR-Chr.10;SHR.BN-(D10Mgh3-Srebf1)/Ipcv; SHR.BN-(D10Mgh3-Srebf1)/Ipcv
Type: congenic
Source: Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic
Origin: 53.7Mbp segment of chr 10 including Srebf1 gene from BN/Crl was introgressed into the SHR/OlaIpcv background
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21045,007,637 - 95,600,487RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01046,570,996 - 98,939,361RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01046,326,015 - 98,640,289RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41046,461,684 - 100,090,454RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table


References

References - curated
# Reference Title Reference Citation
1. Identification of mutated Srebf1 as a QTL influencing risk for hepatic steatosis in the spontaneously hypertensive rat. Pravenec M, etal., Hypertension. 2008 Jan;51(1):148-53. Epub 2007 Dec 10.

Region

Position Markers

Flank 1 / 1 (D10Mgh3)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21095,600,334 - 95,600,487 (+)MAPPER
Rnor_6.01098,939,209 - 98,939,361NCBI
Rnor_5.01098,640,137 - 98,640,289UniSTS
RGSC_v3.410100,090,302 - 100,090,454UniSTS
RGSC_v3.410100,090,301 - 100,090,454RGD
RGSC_v3.110100,104,671 - 100,104,824RGD
Celera1094,250,177 - 94,250,329UniSTS
RH 3.4 Map101080.69RGD
RH 3.4 Map101080.69UniSTS
RH 2.0 Map101218.6RGD
SHRSP x BN Map1077.15RGD
FHH x ACI Map1081.3499RGD
Cytogenetic Map16p16UniSTS

Flank 2 / 1 (Srebf1)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21045,007,637 - 45,029,650 (-)NCBI
mRatBN7.2 Ensembl1045,007,637 - 45,029,650 (-)Ensembl
UTH_Rnor_SHR_Utx1049,707,833 - 49,729,854 (-)NCBI
UTH_Rnor_SHRSP_BbbUtx_1.01049,198,201 - 49,220,219 (-)NCBI
UTH_Rnor_WKY_Bbb_1.01044,701,803 - 44,723,821 (-)NCBI
Rnor_6.01046,570,996 - 46,593,021 (-)NCBI
Rnor_6.0 Ensembl1046,570,996 - 46,593,009 (-)Ensembl
Rnor_5.01046,326,015 - 46,348,035 (-)NCBI
RGSC_v3.41046,461,684 - 46,483,646 (-)NCBI
Celera1044,264,866 - 44,286,830 (-)NCBI
Cytogenetic Map10q22NCBI
Strain QTL Data
Symbol Name Trait
Hpcl2 Hepatic cholesterol level QTL 2 liver cholesterol amount   (VT:0010498)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Carries the BN allele of Srebf1 whereas SHR.BN-(D10Mgh3-D10Rat85)/Ipcv carries the SHR allele of Srebf1 1643359