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Strain: SHR.BN-(D10Mgh3-D10Rat85)/Ipcv

Symbol: SHR.BN-(D10Mgh3-D10Rat85)/Ipcv
Strain: SHR.BN-(D10Mgh3-D10Rat85)
Substrain: Ipcv
RGD ID: 2300215
Citation ID: RRID:RGD_2300215
Ontology ID: RS:0001638
Also Known As: SHR.BN-D10Mgh3/D10Rat85;SHR-Chr.10a;SHR.BN-(D10Mgh3-D10Rat85)/Ipcv; SHR.BN-(D10Mgh3-D10Rat85)/Ipcv; SHR-Chr.10a congenic subline
Type: congenic
Available Source: Not Available
Origination: Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic
Description: Congenic substrain derived from SHR.BN-(D10Mgh3-Srebf1)/Ipcv
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21047,494,000 - 95,600,487RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01049,239,646 - 98,939,361RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01049,018,990 - 98,640,289RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41048,994,688 - 100,090,454RGD_MAPPER_PIPELINERGSC3.4

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table


References - curated
# Reference Title Reference Citation
1. Identification of mutated Srebf1 as a QTL influencing risk for hepatic steatosis in the spontaneously hypertensive rat. Pravenec M, etal., Hypertension. 2008 Jan;51(1):148-53. Epub 2007 Dec 10.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Position Markers

Flank 1 / 1 (D10Mgh3)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21095,600,334 - 95,600,487 (+)MAPPER
Rnor_6.01098,939,209 - 98,939,361NCBI
Rnor_5.01098,640,137 - 98,640,289UniSTS
RGSC_v3.410100,090,302 - 100,090,454UniSTS
RGSC_v3.410100,090,301 - 100,090,454RGD
RGSC_v3.110100,104,671 - 100,104,824RGD
Celera1094,250,177 - 94,250,329UniSTS
RH 3.4 Map101080.69RGD
RH 3.4 Map101080.69UniSTS
RH 2.0 Map101218.6RGD
SHRSP x BN Map1077.15RGD
FHH x ACI Map1081.3499RGD
Cytogenetic Map16p16UniSTS

Flank 2 / 1 (D10Rat85)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21047,494,000 - 47,494,261 (+)MAPPER
Rnor_6.01049,239,646 - 49,239,906NCBI
Rnor_5.01049,018,990 - 49,019,250UniSTS
RGSC_v3.41048,994,688 - 48,994,949RGD
RGSC_v3.41048,994,689 - 48,994,949UniSTS
RGSC_v3.11049,008,312 - 49,008,572RGD
Celera1046,739,198 - 46,739,458UniSTS
RH 3.4 Map10549.6UniSTS
RH 3.4 Map10549.6RGD
RH 2.0 Map10531.8RGD
SHRSP x BN Map1041.9499RGD
Cytogenetic Map10q23UniSTS

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics SHR allele of Srebf1 is responsible for hepatic lipid metabolism 1643359
strain_life_disease SHR allele of Srebf1 decreased the risk of accumulation of liver cholesterol which is dietary induced as compared to SHR.BN-(D10Mgh3-Srebf1)/Ipcv which has Srebf1 allele of BN 1643359

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-27 SHR.BN-(D10Mgh3-D10Rat85)/Ipcv    SHR.BN-(D10Mgh3-D10Rat85)/Ipcv    Name updated 68913 APPROVED
2013-08-27 SHR.BN-(D10Mgh3-D10Rat85)/Ipcv    SHR.BN-(D10Mgh3-D10Rat85)/Ipcv    Name updated 68913 APPROVED