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Strain Registration

Strain: SS-Tg(Atp1a1)48Opaz

Symbol: SS-Tg(Atp1a1)48Opaz
Strain: SS-Tg(Atp1a1)48
Substrain: Opaz
RGD ID: 2292526
Citation ID: RRID:RRRC_00281
Ontology ID: RS:0001483
Also Known As: Dahl SS/Jr-Tg[R-alpha1NK]48; SS-Tg(R-alpha1NK)48Opaz
Type: transgenic
Available Source: Rat Resource and Research Center
Origination: Rat Resource and Research Center
Description: SS/Jr rats were microinjected with rat alpha1 Na,K-ATPase promoter (-1288) 5 flanking regulatory region isolated from Sprague Dawley genomic library); transgene cDNA: Dahl R alpha1 Na,K-ATPase
Coat Color: White
Last Known Status: Cryopreserved Embryo; Cryopreserved Sperm (as of 2019-05-24)





Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. The alpha1 Na,K-ATPase gene is a susceptibility hypertension gene in the Dahl salt-sensitiveHSD rat. Herrera VL, etal., J Clin Invest. 1998 Sep 15;102(6):1102-11.
2. Data registered by the Rat Resource & Research Center Personal Communication with Rat Resource & Research Center
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other these have a longer life span (increased 75.6%) as compared to SS/Jr 2292511
strain_reproduction Litter size: 8-10 2292511

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-05-24 SS-Tg(Atp1a1)48Opaz    SS-Tg(R-alpha1NK)48Opaz    Symbol and/or name change 68913 APPROVED
2012-04-19 SS-Tg(R-alpha1NK)48Opaz    SS-Tg(R-alpha1NK)48Opaz    Name updated 68913 APPROVED
2012-04-19 SS-Tg(R-alpha1NK)48Opaz    SS-Tg(R-alpha1NK)48Opaz    Name updated 68913 APPROVED

Database Acc Id Source(s)
RRRC RRRC:00281 RGD