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Strain Registration

Strain: SD-Tg(SOD1*G93A)26Dwc

Symbol: SD-Tg(SOD1*G93A)26Dwc
Strain: SD-Tg(SOD1*G93A)26
Substrain: Dwc
RGD ID: 2290311
Citation ID: RRID:RGD_2290311
Ontology ID: RS:0001379
Alleles: SOD1
Also Known As: L26H transgenic rats
Type: transgenic
Available Source: Not Available
Origination: Ludwig Institute of Cancer Research, University of California at San Diego, La Jolla, California
Description: SD rats were microinjected with a linear 12 kb EcoRI-BamH1 fragment containing the coding sequence and promoter region of human SOD1 gene with G93A mutation
Last Known Status: Unknown





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Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS). Howland DS, etal., Proc Natl Acad Sci U S A 2002 Feb 5;99(3):1604-9.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics F1 animals with low copy number did not motor neuron diseases 729817