Strain Report - Rat Genome Database

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Strain: F344-TgTn(T2/Bart3)1Ceb

Symbol: F344-TgTn(T2/Bart3)1Ceb
Strain: F344-TgTn(T2/Bart3)1
Substrain: Ceb
RGD ID: 2290057
Citation ID: RRID:RGD_2290057
Ontology ID: RS:0001230
Previously known as: Bart3-1
Type: transgenic
Source: PGA
Origin: The Sleeping Beauty transposon construct, T2/Bart3 consists of inverted terminal repeats separated by a gene trap cassette. The gene trap cassette consists of two splice acceptors, one from adenovirus and one from the mouse Hox9a gene, situated in opposite orientations. Each splice acceptor is followed by stop codons in each reading frame and a polyadenylation signal. Furthermore, the T2/Bart3 transposon harbors a mouse tyrosinase minigene which rescues the phenotype of albino rats, but demonstrates position effect variegated expression.
Last Known Status: Cryopreserved Sperm






References

References - curated
# Reference Title Reference Citation
1. Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon system. Lu B, etal., Mamm Genome. 2007 May;18(5):338-46. Epub 2007 Jun 8.
2. PhysGen Strains PhysGen strains
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other These transgenic animals are no longer available. 629526

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-10-23 F344-TgTn(T2/Bart3)1Ceb    F344-Tg(T2/Bart3)1Ceb    Symbol updated 68687 APPROVED
2015-10-23 F344-TgTn(T2/Bart3)1Ceb    F344-Tg(T2/Bart3)1Ceb    Symbol updated 68687 APPROVED
2015-10-23 F344-TgTn(T2/Bart3)1Ceb    F344-Tg(T2/Bart3)1Ceb    Name updated 68913 APPROVED
2015-10-23 F344-TgTn(T2/Bart3)1Ceb    F344-Tg(T2/Bart3)1Ceb    Name updated 68913 APPROVED
2013-08-13 F344-Tg(T2/Bart3)1Ceb    F344-Tg(T2/Bart3)1Ceb    Name updated 68913 APPROVED
2013-08-13 F344-Tg(T2/Bart3)1Ceb    F344-Tg(T2/Bart3)1Ceb    Name updated 68913 APPROVED