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Strain Registration

Strain: WKY.GHS-(D1Rat32-D1Mit32)

Symbol: WKY.GHS-(D1Rat32-D1Mit32)
Strain: WKY.GHS-(D1Rat32-D1Mit32)
RGD ID: 1598804
Citation ID: RRID:RGD_1598804
Ontology ID: RS:0001597
Also Known As: WKY.GHS-(D1Rat32-D1Mit32); WKY.GHS(RNO1)
Type: congenic
Available Source: Not Available
Origination: Department of Medicine and Physiology, University of Rochester, Rochester New York
Description: GHS females were crossed with WKY males and the heterozygous males were backcrossed to WKY females for 10 generations this resulted in introgressing a 100 cM region of chr 1 which contained the Hc1 QTL
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21244,113,147 - 244,113,296RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01195,598,053 - 265,002,735RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01202,649,657 - 272,443,364RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41112,148,733 - 250,430,505RGD_MAPPER_PIPELINERGSC3.4





Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table

Clinical Measurement
urine calcium excretion rate

References

References - curated
# Reference Title Reference Citation
1. Isolation and confirmation of a calcium excretion quantitative trait locus on chromosome 1 in genetic hypercalciuric stone-forming congenic rats. Hoopes RR Jr, etal., J Am Soc Nephrol. 2006 May;17(5):1292-304. Epub 2006 Apr 12.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D1Rat32)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01195,598,053 - 195,598,217NCBI
Rnor_5.01202,649,657 - 202,649,821UniSTS
RGSC_v3.41112,148,733 - 112,149,024RGD
RGSC_v3.41112,148,806 - 112,148,970UniSTS
RGSC_v3.11112,227,076 - 112,227,367RGD
Celera1105,238,688 - 105,238,852UniSTS
RH 3.4 Map1907.99UniSTS
RH 3.4 Map1907.99RGD
SHRSP x BN Map153.8299RGD
SHRSP x BN Map153.8299UniSTS
FHH x ACI Map155.58RGD
Cytogenetic Map1 RGD

Flank 2 / 1 (D1Mit32)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21244,113,147 - 244,113,296 (+)MAPPER
Rnor_6.01265,002,587 - 265,002,735NCBI
Rnor_5.01272,443,216 - 272,443,364UniSTS
RGSC_v3.41250,430,357 - 250,430,505UniSTS
RGSC_v3.41250,430,356 - 250,430,505RGD
RGSC_v3.11250,690,926 - 250,691,074RGD
Celera1239,924,098 - 239,924,246UniSTS
RH 3.4 Map11623.2RGD
RH 3.4 Map11623.2UniSTS
RH 2.0 Map11220.0RGD
SHRSP x BN Map1139.09RGD
Strain QTL Data
Symbol Name Trait
Hc6 Hypercalciuria QTL 6 urine calcium amount   (VT:0002985)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Higher levels of urine calcium excretion is seen as compared to the parental WKY. 1582396