Strain Report - Rat Genome Database

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Strain: WF.WKY-(D5Uwm68-D5Mit4)/Uwm

Symbol: WF.WKY-(D5Uwm68-D5Mit4)/Uwm
Strain: WF.WKY-(D5Uwm68-D5Mit4)
Substrain: Uwm
RGD ID: 1581641
Citation ID: RRID:RGD_1581641
Ontology ID: RS:0001588
Also Known As: WF.WKY-(D5Uwm68-D5Mit4)/Uwm; WF.WKy-bUwm32-4/D5Mit4; congenic line Y
Type: congenic
Available Source: Not Available
Origination: University of Wisconsin School of Medicine, Madison, Wisconsin
Description: A sub congenic strain derived from the progenitor strain WF.WKY-(D5Wox7-D5Uwm37).
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2574,047,272 - 90,450,412RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0576,401,130 - 93,273,395RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0580,544,432 - 97,315,322RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4577,277,626 - 94,516,069RGD_MAPPER_PIPELINERGSC3.4

Experimental Data Annotations    Click to see Annotation Detail View

Rat Strain
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
WF.WKY-(D5Uwm68-D5Mit4)/UwmRatWF.WKY-(D5Uwm68-D5Mit4)/Uwm  IEA 7241799 RGD 

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
WF.WKY-(D5Uwm68-D5Mit4)/UwmRatmammary gland integrity trait  EXP 1559294 RGD 


References - curated
# Reference Title Reference Citation
1. RGD Strain RSO annotation pipeline RGD Automated Pipelines
2. Fine mapping reveals multiple loci and a possible epistatic interaction within the mammary carcinoma susceptibility quantitative trait locus, Mcs5. Samuelson DJ, etal., Cancer Res. 2005 Nov 1;65(21):9637-42.
3. Mcs5c: a mammary carcinoma susceptibility locus located in a gene desert that associates with tenascin C expression. Veillet AL, etal., Cancer Prev Res (Phila). 2011 Jan;4(1):97-106.


Position Markers

Flank 1 / 1 (D5Uwm68)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2574,047,272 - 74,047,522 (+)MAPPER
Rnor_6.0576,401,130 - 76,401,379NCBI
Rnor_5.0580,544,432 - 80,544,681UniSTS
RGSC_v3.4577,277,626 - 77,277,875UniSTS
Celera572,868,397 - 72,868,628UniSTS
Cytogenetic Map5q24UniSTS

Flank 2 / 1 (D5Mit4)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2590,450,144 - 90,450,412 (+)MAPPER
Rnor_6.0593,273,130 - 93,273,395NCBI
Rnor_5.0597,315,057 - 97,315,322UniSTS
RGSC_v3.4594,515,803 - 94,516,069RGD
RGSC_v3.4594,515,804 - 94,516,069UniSTS
RGSC_v3.1594,520,917 - 94,521,182RGD
Celera589,134,454 - 89,134,719UniSTS
RH 3.4 Map5696.7RGD
RH 3.4 Map5696.7UniSTS
Cytogenetic Map5q31UniSTS
Strain QTL Data
Symbol Name Trait
Mcs14 Mammary carcinoma susceptibility QTL 14 mammary gland integrity trait   (VT:0010552)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease Averaged 3.5 mammary carcinomas per rat (WKY homozygous), which is statistically reduced from WF-homozygous females and the WF parental strains. 1559294

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-23 WF.WKY-(D5Uwm68-D5Mit4)/Uwm    WF.WKY-(D5Uwm68-D5Mit4)/Uwm    Name updated 68913 APPROVED
2012-10-23 WF.WKY-(D5Uwm68-D5Mit4)/Uwm    WF.WKY-(D5Uwm68-D5Mit4)/Uwm    Name updated 68913 APPROVED