Department of Physiology, Medical College of Wisconsin, Milwaukee
This congenic strain contains a LEW chromosome 5 segment transferred to the Dahl salt sensitive background. The strain was originally developed by Drs. Rapp and M. R. Garrett at the Medical University of Ohio and has also been maintained by brother-sister mating at the Medical College of Wisconsin for more than 20 generations.
transferred chromosome 5 segment contains a region from RNO5 from markers D5Rat130 to D5Rat108 that excludes the CYP4A genes and is 5 Mbp shorter than the transferred chromosome 5 segment in congenic strain SS.LEW-(D5Rat130-D5Rat31)/JrMcwi