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Strain Registration

Strain: GH/OmrMcwi

Symbol: GH/OmrMcwi
Strain: GH
Substrain: OmrMcwi
RGD ID: 1579686
Citation ID: RRID:RGD_1579686
Ontology ID: RS:0001108
Also Known As: MDC-03-11
Type: inbred
Available Source: Not Available
Origination: PhysGen
Description: This colony was established from rats of Wistar origin. This is an hysterectomy-derived colony at the University of Otago, which was established from the Wellcome Institute colony at generation 79. These have been inbred for over 90 generations. These were given to Dr. Howard Jacob in 1999 and have been bred in Medical College of Wisconsin since then.
Last Known Status: Live Animals; Cryopreserved Embryo





Phenotype Values via Phenominer Click to see Annotation Detail View

Related Phenotype Data for Term "GH/OmrMcwi" (RS:0001108)

Rat Strains:
Clinical Measurements:
Experimental Conditions:
Measurement Methods:

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table

Clinical Measurement
heart rate
left ventricular diastolic blood pressure
left ventricular systolic blood pressure
mean arterial blood pressure
body weight
body temperature
left ventricular developed pressure
red blood cell count
blood hemoglobin level
blood neutrophil count
blood lymphocyte count
blood monocyte count
blood eosinophil count
hematocrit
mean corpuscular volume
plasma anion gap
heart wet weight
heart weight to body weight ratio
lung dry weight to body weight ratio
heart right ventricle weight to left ventricle weight ratio
plasma renin activity level
minute ventilation
arterial blood flow rate
tidal volume
partial pressure of blood carbon dioxide (Pco2)
percent change in ventilation
respiration rate
mean corpuscular hemoglobin
mean corpuscular hemoglobin concentration
absolute change in partial pressure of blood carbon dioxide
absolute change in partial pressure of blood oxygen
absolute change in blood pH
serum total cholesterol level
total white blood cell count
serum total bilirubin level
blood pH
partial pressure of blood oxygen
serum bicarbonate level
serum chloride level
serum potassium level
serum sodium level
serum calcium level
percent change in respiration rate
percent change in tidal volume
absolute change in mean arterial blood pressure
absolute change in heart rate
plasma creatinine level
serum phosphate level
serum glucose level
serum albumin level
serum alanine aminotransferase activity level
serum alkaline phosphatase activity level
serum aspartate aminotransferase activity level
serum urea nitrogen level
serum total protein level
time to onset of heart contraction
time to peak heart contraction
heart contraction pressure
heart left ventricle infarction weight to total heart left ventricle weight ratio
absolute change in body temperature
calculated pulmonary vascular resistance normalized to body weight
FAPGG metabolism-surface area product
methylene blue metabolism-surface area product without auto-oxidation
methylene blue metabolism-surface area product after auto-oxidation
methylene blue to FAPGG metabolism-surface area product ratio
dose of methacholine at which pulmonary conductance is half its pretreatment value
fractional change in blood vessel diameter per unit change in intravascular pressure
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50)
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50)
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)
concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50)
logarithm of the concentration of sodium nitroprusside at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50)
maximum contractile force per wet weight of aorta
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
hypoxia-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
percent change in heart rate
percent change in arterial blood flow rate
percent change in left ventricular developed pressure
percent change in left ventricular systolic blood pressure
urine total protein excretion rate
urine albumin excretion rate
urine sodium excretion rate
creatinine clearance
heart effluent lactate dehydrogenase activity level normalized to heart weight
serum globulin level

References

References - curated
# Reference Title Reference Citation
1. RGD Strain RSO annotation pipeline RGD Automated Pipelines
2. SNP and haplotype mapping for genetic analysis in the rat. Saar K, etal., Nat Genet. 2008 May;40(5):560-6.
3. Sequence analysis of the complete mitochondrial DNA in 10 commonly used inbred rat strains. Schlick NE, etal., Am J Physiol Cell Physiol. 2006 Dec;291(6):C1183-92. Epub 2006 Jul 19.

Region

Strain Samples in RGD with Damaging Variants (Polyphen)
AssemblySample 
RGSC_v3.4 GH/OmrMcwi (MCW) View Damaging Variants
Rnor_5.0 GH/OmrMcwi (MCW) View Damaging Variants
Rnor_6.0 GH/OmrMcwi (MCW) View Damaging Variants


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-12 GH/OmrMcwi    GH/OmrMcwi    Name updated 68913 APPROVED
2013-08-12 GH/OmrMcwi    GH/OmrMcwi    Name updated 68913 APPROVED