Strain Report - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Strain Registration

Strain: SD-Tg(ICAM2-DAF)AngRrrc

Symbol: SD-Tg(ICAM2-DAF)AngRrrc
Strain: SD-Tg(ICAM2-DAF)
Substrain: AngRrrc
RGD ID: 1566460
Citation ID: RRID:RRRC_00051
Ontology ID: RS:0001397
Also Known As: SD-Tg(ICAM2-DAF)Ang/Rrrc
Type: transgenic
Available Source: Rat Resource and Research Center
Origination: Rat Resource and Research Center
Description: Embryos were microinjected with DNA containing the human DAF(decay-acceletating factor) gene under control of the human ICAM2 promoter.
Coat Color: White
Last Known Status: Cryopreserved Embryo; Cryopreserved Sperm






References

References - curated
# Reference Title Reference Citation
1. Protection against hyperacute xenograft rejection of transgenic rat hearts expressing human decay accelerating factor (DAF) transplanted into primates. Charreau B, etal., Mol Med. 1999 Sep;5(9):617-30.
2. Data registered by the Rat Resource & Research Center Personal Communication with Rat Resource & Research Center
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_other These rats were used as heart donors to detemine their resistance against complement (C)-mediated rejection by non-human primates. 1559415
strain_other Uniformly expressed in the endothelium of all blood vessels. 1559415

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-04-18 SD-Tg(ICAM2-DAF)AngRrrc    SD-Tg(ICAM2-DAF)AngRrrc    Name updated 68913 APPROVED
2012-04-18 SD-Tg(ICAM2-DAF)AngRrrc    SD-Tg(ICAM2-DAF)AngRrrc    Name updated 68913 APPROVED

Database Acc Id Source(s)
RRRC RRRC:00051 RGD