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Strain: F344-Tg(CAG-ACE2)057Bryd

Symbol: F344-Tg(CAG-ACE2)057Bryd
Strain: F344-Tg(CAG-ACE2)057
Substrain: Bryd
RGD ID: 155269040
Citation ID: RRID:RRRC_00946
Ontology ID: RS:0005167
Also Known As: RRRC:00946
Type: transgenic
Available Source: Deposited at Rat Resource and Research Center
Description: The human ACE2 gene was placed under control of the synthetic CAG promoter which allows ubiquitous expression of the gene. Based on droplet digital PCR analysis, the strain carries only 1 copy of the transgene. The integration site is unknown. These rats express the human ACE2 gene. The encoded protein is a functional receptor for the spike glycoprotein of several human coronaviruses including SARS-CoV-2, the causative agent of coronavirus disease-2019 (COVID-19).
Coat Color: white
Last Known Status: Live Animals (as of 2022-10-11)






References

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Additional Information

Database Acc Id Source(s)
RRRC RRRC:00946 RGD