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Strain: BN/Seac

Symbol: BN/Seac
Strain: BN
Substrain: Seac
RGD ID: 1549801
Citation ID: RRID:RGD_1549801
Ontology ID: RS:0000430
Previously known as: BN/fMaiSeac; NBRP Rat No: 0664
Type: inbred
Source: Seac Yoshitomi, LTD, Fukuoka, Japan, National BioResource Project for the Rat in Japan
Origin: Seac Yoshitomi, LTD, Fukuoka, Japan
Inbred Generations: F86
Last Known Status: Cryopreserved Sperm
Research Usage Behavior; Ophthalmology





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Clinical Measurement
heart rate
systolic blood pressure
body weight
body temperature
red blood cell count
blood hemoglobin level
white blood cell count
platelet count
hematocrit
mean corpuscular volume
plasma glucose level
plasma aspartate aminotransferase activity level
plasma alanine aminotransferase activity level
plasma alkaline phosphatase activity level
plasma total protein level
plasma albumin level
plasma phosphate level
plasma chloride level
plasma sodium level
plasma potassium level
heart wet weight
heart weight to body weight ratio
both kidneys wet weight
lung wet weight
urine potassium level
urine sodium level
brain weight to body weight ratio
both kidneys wet weight as percentage of body weight
liver weight as percentage of body weight
spleen weight to body weight ratio
brain wet weight
lung weight to body weight ratio
liver wet weight
both adrenal glands wet weight
spleen wet weight
both testes wet weight
activated partial thromboplastin time
prothrombin time
timed urine volume
mean corpuscular hemoglobin
mean corpuscular hemoglobin concentration
blood glucose level area under curve (AUC)
serum triglyceride level
serum total cholesterol level
blood basophil count to total leukocyte count ratio
blood eosinophil count to total leukocyte count ratio
blood lymphocyte count to total leukocyte count ratio
blood monocyte count to total leukocyte count ratio
total plasma calcium level
urine chloride level
plasma creatinine level
plasma triglyceride level
plasma total cholesterol level
plasma urea nitrogen level
both adrenal glands weight to body weight ratio
plasma high density lipoprotein cholesterol level
plasma low density lipoprotein cholesterol level
both testes wet weight to body weight ratio
white adipose tissue weight to body weight ratio
urine sodium excretion rate to body weight ratio
timed urine volume to body weight ratio
urine chloride excretion rate to body weight ratio
urine potassium excretion rate to body weight ratio
plasma total bilirubin level
blood segmented neutrophil count to total leukocyte count ratio
blood band neutrophil count to total leukocyte count ratio
non-specified leukocyte count to total leukocyte count ratio
plasma albumin to plasma total protein ratio

References

References - curated
# Reference Title Reference Citation
1. Genetic analysis of diet-induced hypercholesterolemia in exogenously hypercholesterolemic (ExHC) rats. Asahina M, et al., J Lipid Res 46(10):2289-2294, 2005.
2. Identification of SMEK2 as a candidate gene for regulation of responsiveness to dietary cholesterol in rats. Asahina M, etal., J Lipid Res. 2008 Aug 27.
3. Genetic analysis for diabetes in a new rat model of nonobese type 2 diabetes, Spontaneously Diabetic Torii rat. Masuyama T, etal., Biochem Biophys Res Commun 2003 Apr 25;304(1):196-206.
4. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
5. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Strain QTL Data
Symbol Name Trait
Gluco13 Glucose level QTL 13 blood glucose amount   (VT:0000188)    
Gluco14 Glucose level QTL 14 blood glucose amount   (VT:0000188)    
Gluco15 Glucose level QTL 15 blood glucose amount   (VT:0000188)    
Scl44 Serum cholesterol level QTL 44 blood cholesterol amount   (VT:0000180)    
Scl45 Serum cholesterol level QTL 45 blood cholesterol amount   (VT:0000180)    
Scl46 Serum cholesterol level QTL 46 blood cholesterol amount   (VT:0000180)    
Scl47 Serum cholesterol level QTL 47 blood cholesterol amount   (VT:0000180)    
Scl48 Serum cholesterol level QTL 48 blood cholesterol amount   (VT:0000180)    

Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-04-17 BN/Seac    BN/Seac    Name updated 68913 APPROVED
2014-04-17 BN/Seac    BN/Seac    Name updated 68913 APPROVED