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Strain Registration

Strain: SHRSP.SHR-(rs197197017 -rs198445122)/Utx

Symbol: SHRSP.SHR-(rs197197017 -rs198445122)/Utx
Strain: SHRSP.SHR-(rs197197017 -rs198445122)
Substrain: Utx
RGD ID: 150340617
Citation ID: RRID:RGD_150340617
Ontology ID: RS:0005009
Also Known As: SHR-A3(Stim1-B2); SHRSP.SHR-(rs106374972-rs106170276)/Utx; SHRSP.SHR-(rs197197017 -rs198445122)/Utx
Type: congenic
Available Source: Not Available
Origination: University of Texas, Houston, TX
Description: A congenic strain made by introducing B2 fragment (a segment of chromosome 1, 154.7 Mb - 203 Mb) from SHR/Utx into SHRSP/BbbUtx.The B2 fragment contains wild-type Stim1 as confirmed by sequencing.
Last Known Status: Unknown





References

References - curated
# Reference Title Reference Citation
1. Natural genetic variation in Stim1 creates stroke in the spontaneously hypertensive rat. Dhande IS, etal., Genes Immun. 2020 May;21(3):182-192. doi: 10.1038/s41435-020-0097-5. Epub 2020 Apr 17.
2. Stim1 Polymorphism Disrupts Immune Signaling and Creates Renal Injury in Hypertension. Dhande IS, etal., J Am Heart Assoc. 2020 Mar 3;9(5):e014142. doi: 10.1161/JAHA.119.014142. Epub 2020 Feb 20.

Region

Position Markers

Flank 1 / 1 (rs197197017)		 No map positions available.

Flank 2 / 1 (rs198445122)		 No map positions available.

Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-10-04 SHRSP.SHR-(rs197197017 -rs198445122)/Utx    SHRSP.SHR-(rs106374972-rs106170276)/Utx    Symbol and/or name change 68913 APPROVED
2021-09-10 SHRSP.SHR-(rs106374972-rs106170276)/Utx    SHRSP.SHR-(rs149735373-rs106170276)/Utx    Symbol and/or name change 68913 APPROVED