Strain Report - Rat Genome Database

Name: F344- Trpc4 Tn(sb-T2/Bart3)2.192Mcwi-/-
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain Registration

General

Strain: F344-Trpc4^{Tn(sb-T2/Bart3)2.192Mcwi-/-}
Symbol:	F344-Trpc4^{Tn(sb-T2/Bart3)2.192Mcwi-/-}
Strain:	F344-Trpc4^{Tn(sb-T2/Bart3)2.192-/-}
Substrain:	Mcwi
RGD ID:	14696720
Citation ID:	RRID:RGD_14696720
Ontology ID:	RS:0004749
Previously known as:	F344-Trpc4^{Tn(sb-T2/Bart3)2.192Mcwi-/+}; TRPC4-/-
Type:	mutant
Source:	PhysGen, Transposagen, Rat Resource and Research Center
Origin:	These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169). This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 1st intron of the Trpc4 gene. The heterozygotes were intercrossed to produce the homozygous mutant.
Last Known Status:	Unknown

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Visceral Pain (IMP)

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Clinical Measurement

number of lower body licking events

number of abdominal retractions

ventricular late potential

References

References - curated


1.	Westlund KN, etal., Neuroscience. 2014 Mar 14;262:165-75. doi: 10.1016/j.neuroscience.2013.12.043. Epub 2014 Jan 3.

Region

Additional Information

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-07-19	F344-Trpc4^{Tn(sb-T2/Bart3)2.192Mcwi-/-}		F344-Trpc4^{Tn(sb-T2/Bart3)2.192Mcwi-/+}		Symbol and/or name change	68913	APPROVED

External Database Links

Database	Acc Id	Source(s)
RRRC	RRRC:00344	RGD

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Strain: F344-Trpc4^{Tn(sb-T2/Bart3)2.192Mcwi-/-}

Related Phenotype Data for Term "F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi-/-" (RS:0004749)

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Strain: F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi-/-

Related Phenotype Data for Term "F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi-/-" (RS:0004749)

Strain: F344-Trpc4^{Tn(sb-T2/Bart3)2.192Mcwi-/-}