Strain Report - Rat Genome Database

Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Strain: SD.DA-Pex1Tm(G843D-FRT-CAG-Pac-FRT)1Qly

Symbol: SD.DA-Pex1Tm(G843D-FRT-CAG-Pac-FRT)1Qly
Strain: SD.DA-Pex1Tm(G843D-FRT-CAG-Pac-FRT)1
Substrain: Qly
RGD ID: 14695030
Citation ID: RRID:RRRC_00846
Ontology ID: RS:0004725
Also known as: Pex1-Tm(G843D-FRT-CAG-Pac-FRT)Qly; RRRC:00846
Type: mutant
Source: Rat Resource and Research Center
Origin: This strain was made by electroporation of DAc8 embryonic stem cells with a targeting vector containing 5.8kb 5' and 1.7kb 3' homology arms. A G843D point mutation is introduced into the Pex1 gene. The 12th and 13th exons are flanked with two loxP sites. A FRT-CAG-Pac-FRT cassette is inserted into the intron between Pex1 13th and 14th exon. This strain mimics the Peroxisomal Disorders. Heterozygote does not show any abnormalities.
Last Known Status: Unknown



Additional Information