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Strain: SD-Fhem1+/+

Symbol: SD-Fhem1+/+
Strain: SD-Fhem1+/SD-Fhem1+
RGD ID: 13792795
Citation ID: RRID:RGD_13792795
Ontology ID: RS:0004633
Also Known As: SD-Fh^[em1+/+]
Type: mutant
Available Source: Not Available
Description: A pair of TALENs targeting exon 1 of the Fh gene was injected into SD embryos to create Fh knock out mutants. The resulting mutation was an 11-bp deletion (acacctttggt) on exon 1 that caused premature stop of FH protein. Breeding of Fh +/- rats was done to generate wildtype (Fh+/+)and Fh (+/-). No homozygous mutant were observed.
Genetic Status: Wild Type
Last Known Status: Unknown





References

References - curated
# Reference Title Reference Citation
1. Generation of TALEN-mediated FH knockout rat model. Yu D, etal., Oncotarget. 2016 Sep 20;7(38):61656-61669. doi: 10.18632/oncotarget.11429.

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