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Strain: SD-Trpv1em1Sage+/+

Symbol: SD-Trpv1em1Sage+/+
Strain: SD-Trpv1em1+/ Trpv1em1+
Substrain: Sage
RGD ID: 13792705
Citation ID: RRID:RGD_13792705
Ontology ID: RS:0004630
Type: mutant
Source: Not Available
Origin: These ZFN mutant rats were produced by injecting zinc finger nuclease targeting exon 13 of rat Trpv1 into Sprague Dawley embryos. A 2-bp (CA) frameshift deletion in exon 13 was created ( SD-Trpv1em1Sage-/-). This wild type mutant is the wild type offspring from the cross of heterozygous mutants.
Genetic Status: Wild Type
Last Known Status: Unknown

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
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References - curated
# Reference Title Reference Citation
1. Transient Receptor Potential Vanilloid 1 Regulates Mitochondrial Membrane Potential and Myocardial Reperfusion Injury. Hurt CM, etal., J Am Heart Assoc. 2016 Sep 26;5(9). pii: JAHA.116.003774. doi: 10.1161/JAHA.116.003774.
2. Hypernatremia-induced vasopressin secretion is not altered in TRPV1-/- rats. Tucker AB and Stocker SD, Am J Physiol Regul Integr Comp Physiol. 2016 Sep 1;311(3):R451-6. doi: 10.1152/ajpregu.00483.2015. Epub 2016 Jun 22.


Additional Information