Strain Report - Rat Genome Database

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Strain: MR/Har

Symbol: MR/Har
Strain: MR
Substrain: Har
Full Name: Maudsely reactive
RGD ID: 1358632
Citation ID: RRID:RRRC_00691
Ontology ID: RS:0000588
Previously known as: MR/Har/Bliz
Type: inbred
Source: Center for Developmental and Health Genetics, Pennsylvania State University, Pennsylvania. Rat Resource and Research Center
Origin: This strain has been selected for high open-field defecation (a test of emotional reactivity). The underlying genetic basis for this phenotype is not known. Originally selected by Broadhurst in 1954 for high open-field defacation (OFD) response in an open field. By Broadhurst to Harrington at the University of Northern Iowa at generation 25 in 1965.
Coat Color: albino
Last Known Status: Cryopreserved Embryo (as of 2019-02-20)


References - curated
# Reference Title Reference Citation
1. The Maudsley Reactive and Nonreactive strains: a new perspective. Blizard DA and Adams N, Behav Genet 2002 Sep;32(5):277-99.
2. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_behavior Show increased motor activation as compared to MNRA/Har to a low dose of alcohol. Females exhibit greater motor activation 1358541
Database Acc Id Source(s)