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Strain Registration

Strain: DA/K

Symbol: DA/K
Strain: DA
Substrain: K
Full Name: Dark Agouti/Karlsburg
RGD ID: 1357345
Citation ID: RRID:RGD_1357345
Ontology ID: RS:0000243
Type: inbred
Source: Dept. of Laboratory Animal Science, Inst. of Pathology, University of Greifswald,D-17495, Karlsburg, Germany
Origin: Dark agouti rats which were bred and housed in Dept. of Laboratory Animal Science, Karlsburg, Germany
Last Known Status: Unknown





Experimental Data Annotations    Click to see Annotation Detail View

Rat Strain
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
DA/K  IEA 7241799 RGD 

Vertebrate Trait
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
blood cholesterol amount  EXP 619689 RGD 
blood glucose amount  EXP 619689 RGD 
blood HDL cholesterol amount  EXP 619689 RGD 
blood insulin amount  EXP 619689 RGD 
blood leptin amount  EXP 1357168; 619689 RGD 
blood triglyceride amount  EXP 1357168; 619689 RGD 
body mass  EXP 1357168; 619689 RGD 
inguinal fat pad mass  EXP 1357168 RGD 

References

References - curated
# Reference Title Reference Citation
1. Involvement of cocaine-amphetamine regulated transcript in the differential feeding responses to nociceptin/orphanin FQ in dark agouti and Wistar Ottawa Karlsburg W rats. Filippetti R, etal., Peptides. 2007 Oct;28(10):1966-73. Epub 2007 Aug 10.
2. Sex-specific and sex-independent quantitative trait loci for facets of the metabolic syndrome in WOKW rats. Kloting I, etal., Biochem Biophys Res Commun 2001 Jun 1;284(1):150-6.
3. Genetic dissection of the syndrome X in the rat. Kovacs P, etal., Biochem Biophys Res Commun 2000 Mar 24;269(3):660-5.
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Strain QTL Data
Symbol Name Trait
Bw41 Body weight QTL 41 body mass   (VT:0001259)    
Bw42 Body weight QTL 42 body mass   (VT:0001259)    
Bw43 Body weight QTL 43 body mass   (VT:0001259)    
Bw44 Body weight QTL 44 body mass   (VT:0001259)    
Bw45 Body weight QTL 45 body mass   (VT:0001259)    
Bw46 Body weight QTL 46 body mass   (VT:0001259)    
Bw62 Body weight QTL62 inguinal fat pad mass   (VT:0010424)    
Bw83 Body weight QTL 83 body mass   (VT:0001259)    
Bw84 Body weight QTL 84 body mass   (VT:0001259)    
Gluco39 Glucose level QTL 39 blood glucose amount   (VT:0000188)    
Gluco40 Glucose level QTL 40 blood glucose amount   (VT:0000188)    
Insul11 Insulin level QTL 11 blood insulin amount   (VT:0001560)    
Scl60 Serum cholesterol level QTL 60 blood cholesterol amount   (VT:0000180)    
Scl61 Serum cholesterol level QTL 61 blood HDL cholesterol amount   (VT:0000184)    
Slep3 Serum leptin concentration QTL 3 blood leptin amount   (VT:0005667)    
Slep4 Serum leptin concentration QTL 4 blood leptin amount   (VT:0005667)    
Slep5 Serum leptin concentration QTL 5 blood leptin amount   (VT:0005667)    
Slep6 Serum leptin concentration QTL 6 blood leptin amount   (VT:0005667)    
Stl14 Serum triglyceride level QTL 14 blood triglyceride amount   (VT:0002644)    
Stl17 Serum triglyceride level QTL 17 blood triglyceride amount   (VT:0002644)    
Stl22 Serum triglyceride level QTL 22 blood triglyceride amount   (VT:0002644)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_drgs_chems Nociceptin/orphanin FQ injection into the lateral brain ventricle significantly increases the food intake in 4 hours 1642517