Strain Report - Rat Genome Database
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Strain: CDR/Ygl

Symbol: CDR/Ygl
Strain: CDR
Substrain: Ygl
RGD ID: 1357181
RRID: RGD_1357181
Ontology ID: RS:0000180
Also known as: MDC-01-89; CDr/y
Type: inbred
Source: Hebrew University Hospital and Hadassah-Hebrew Medical College, Jerusalem, Israel; Israeli Rat Genome Center, Ashkelon, Israel
Origin: Cohen rats that had an oral tolerance test with blood glucose levels <180mg/dl were selected. More stringent criteria was set during the secondary inbreeding: rats with blood glucose levels <140mg/dl were selected. Brother and sister mating was carried on for 10 additional generations.
Last Known Status: Unknown





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References


Region

Strain QTL Data
Symbol Name Trait
Gluco32 Glucose level QTL 32 blood glucose amount   (VT:0000188)    
Gluco33 Glucose level QTL 33 blood glucose amount   (VT:0000188)    
Gluco34 Glucose level QTL 34 blood glucose amount   (VT:0000188)    
Gluco61 Glucose level QTL 61 blood glucose amount   (VT:0000188)    
Gluco62 Glucose level QTL 62 blood glucose amount   (VT:0000188)    
Gluco63 Glucose level QTL 63 blood glucose amount   (VT:0000188)    
Insul22 Insulin level QTL 22 blood insulin amount   (VT:0001560)    
Pancm3 Pancreatic morphology QTL 3 pancreas mass   (VT:0010144)    
Pancm4 Pancreatic morphology QTL 4 pancreas mass   (VT:0010144)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Males that were fed the regular rat diet showed a 3 fold increase in their weight at 4-6 months whereas the males that were fed diabetogenic diet grew at the same rate. Females did not show difference in growth curves irrespective of diet. 1342468
strain_characteristics They are resistant to the diabetogenic diet (high-sucrose low-copper). 1342468
strain_characteristics Insulin levels were higher in animals that were fed diabetogenic diet than the ones fed regular diet. 1342468