Experimental Data Annotations Click to see Annotation Detail View
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Experimental Data Annotations Click to see Annotation Detail View
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# | Reference Title | Reference Citation |
1. | GENDER-SPECIFIC GENETIC DISSECTION OF DIABETES IN A RODENT MODEL IDENTIFIES ICA1 AND NDUFA4 AS MAJOR CANDIDATE GENES. | Barkalifa R, etal., Physiol Genomics. 2010 Jun 8. |
2. | RGD Strain RSO annotation pipeline | RGD Automated Pipelines |
3. | SNP and haplotype mapping for genetic analysis in the rat. | Saar K, etal., Nat Genet. 2008 May;40(5):560-6. |
4. | The newly inbred cohen diabetic rat: a nonobese normolipidemic genetic model of diet-induced type 2 diabetes expressing sex differences. | Weksler-Zangen S, etal., Diabetes 2001 Nov;50(11):2521-9. |
5. | A novel mutation in the NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 4 (Ndufa4) gene links mitochondrial dysfunction to the development of diabetes in a rodent model. | Yagil C, etal., Dis Model Mech. 2018 Nov 20;11(11). pii: dmm.036699. doi: 10.1242/dmm.036699. |
6. | Metabolic and genomic dissection of diabetes in the Cohen rat. | Yagil C, etal., Physiol Genomics. 2007 Apr 24;29(2):181-92. Epub 2007 Jan 9. |
7. | Unmasking of proteinuria in the course of genetic dissection of nonproteinuric diabetic nephropathy. | Yagil Y, etal., Physiol Genomics. 2014 Jan 1;46(1):29-38. doi: 10.1152/physiolgenomics.00133.2013. Epub 2013 Nov 5. |
Symbol | Name | Trait |
Gluco32 | Glucose level QTL 32 |
blood glucose amount (VT:0000188)
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Gluco33 | Glucose level QTL 33 |
blood glucose amount (VT:0000188)
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Gluco34 | Glucose level QTL 34 |
blood glucose amount (VT:0000188)
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Gluco61 | Glucose level QTL 61 |
blood glucose amount (VT:0000188)
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Gluco62 | Glucose level QTL 62 |
blood glucose amount (VT:0000188)
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Gluco63 | Glucose level QTL 63 |
blood glucose amount (VT:0000188)
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Insul22 | Insulin level QTL 22 |
blood insulin amount (VT:0001560)
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Pancm3 | Pancreatic morphology QTL 3 |
pancreas mass (VT:0010144)
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Pancm4 | Pancreatic morphology QTL 4 |
pancreas mass (VT:0010144)
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Note Type | Note | Reference |
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strain_characteristics | Males that were fed the regular rat diet showed a 3 fold increase in their weight at 4-6 months whereas the males that were fed diabetogenic diet grew at the same rate. Females did not show difference in growth curves irrespective of diet. | 1342468 |
strain_characteristics | They are resistant to the diabetogenic diet (high-sucrose low-copper). | 1342468 |
strain_characteristics | Insulin levels were higher in animals that were fed diabetogenic diet than the ones fed regular diet. | 1342468 |