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Strain: F344.BN-(D5Rat1-D5Mit5)/Dlw

Symbol: F344.BN-(D5Rat1-D5Mit5)/Dlw
Strain: F344.BN-(D5Rat1-D5Mit5)
Substrain: Dlw
RGD ID: 1331830
Citation ID: RRID:RGD_1331830
Ontology ID: RS:0001297
Previously known as: F344.BN-Edpm5; F344.BN-(D5Mgh3-D5Mit7)/Dlw; F344.BN-(D5Rat1-D5Mit5)/Dlw
Type: congenic
Source: Department of Biological Sciences, Oakland University, Rochester, MI
Origin: This congenic strain carries the BN Edpm5 QTL on an F344 background. This strain is maintained at Oakland University, Rochester, MI, USA
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2534,730,116 - 104,251,008RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0535,225,432 - 108,092,802RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0539,876,314 - 112,058,005RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4535,911,094 - 109,163,425RGD_MAPPER_PIPELINERGSC3.4





References

References - curated
# Reference Title Reference Citation
1. The Edpm5 locus prevents the "angiogenic switch" in an estrogen-induced rat pituitary tumor. Pandey J, etal., Carcinogenesis 2004 May 27;.
2. Localization of Eutr2, a locus controlling susceptibility to DES-induced uterine inflammation and pyometritis, to RNO5 using a congenic rat strain. Pandey J, etal., Mamm Genome. 2005 Nov;16(11):865-72. Epub 2005 Nov 11.
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D5Rat1)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2534,730,116 - 34,730,278 (+)MAPPER
Rnor_6.0535,225,432 - 35,225,593NCBI
Rnor_5.0539,876,314 - 39,876,475UniSTS
RGSC_v3.4535,911,094 - 35,911,256RGD
RGSC_v3.4535,911,095 - 35,911,256UniSTS
RGSC_v3.1535,911,273 - 35,911,435RGD
Celera533,766,190 - 33,766,351UniSTS
SHRSP x BN Map520.3999UniSTS
SHRSP x BN Map520.3999RGD

Flank 2 / 1 (D5Mit5)
Rat AssemblyChrPosition (strand)Source
mRatBN7.25104,250,862 - 104,251,008 (+)MAPPER
Rnor_6.05108,092,659 - 108,092,802NCBI
Rnor_5.05112,057,862 - 112,058,005UniSTS
RGSC_v3.45109,163,281 - 109,163,425RGD
RGSC_v3.45109,163,282 - 109,163,425UniSTS
RGSC_v3.15109,168,508 - 109,168,651RGD
Celera5102,964,236 - 102,964,379UniSTS
RH 3.4 Map5744.8UniSTS
RH 3.4 Map5744.8RGD
RH 2.0 Map5676.5RGD
SHRSP x BN Map558.1599RGD
FHH x ACI Map552.48RGD
Cytogenetic Map5q32UniSTS
Strain QTL Data
Symbol Name Trait
Eutr2 Estrogen induced uterine response QTL 2 uterus integrity trait   (VT:0010575)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease This congenic strain develops estrogen-induced pituitary tumors like parental strain F344 but has a non-angiogenic phenotype unlike the F344 strain 1300042
strain_life_disease This congenic strain exhibits a profound increase in DES-induced uterine inflammation and pyometritis compared to the F344 parental strain 1559291