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Strain: DA.ACI-(D10Rat2-D10Rat29)/Kini

Symbol: DA.ACI-(D10Rat2-D10Rat29)/Kini
Strain: DA.ACI-(D10Rat2-D10Rat29)
Substrain: Kini
RGD ID: 1331816
Citation ID: RRID:RGD_1331816
Ontology ID: RS:0000199
Also Known As: DA.ACI-(D10Rat2-D10Rat29)/Kini; NBRP Rat No: 0697; DA.ACI-Eae18
Type: congenic
Available Source: National BioResource Project for the Rat in Japan
Origination: Neuroimmunology Unit, Center for Molecular Medicine, Stockholm, Sweden
Description: (DA x ACI) x DA backcross in the second generation transfered 40 cM of DNA from ACI to DA.
Coat Color: agouti
Inbred Generations: N6F1
Last Known Status: Cryopreserved Sperm
Research Usage Neurobiology; Immunology
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.210107,057,622 - 107,057,807RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.01067,988,035 - 110,992,275RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01067,642,121 - 110,568,670RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41068,842,878 - 68,843,272RGD_MAPPER_PIPELINERGSC3.4





References

References - curated
# Reference Title Reference Citation
1. Congenic mapping confirms a locus on rat chromosome 10 conferring strong protection against myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis. Jagodic M, etal., Immunogenetics 2001 Jul;53(5):410-5.
2. An advanced intercross line resolves Eae18 into two narrow quantitative trait loci syntenic to multiple sclerosis candidate loci. Jagodic M, etal., J Immunol 2004 Jul 15;173(2):1366-73.
3. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D10Rat2)
Rat AssemblyChrPosition (strand)Source
mRatBN7.210107,057,622 - 107,057,807 (+)MAPPER
Rnor_6.010110,992,091 - 110,992,275NCBI
Rnor_5.010110,568,486 - 110,568,670UniSTS
Celera10105,592,664 - 105,592,836UniSTS
SHRSP x BN Map1093.86RGD
SHRSP x BN Map1093.86UniSTS

Flank 2 / 1 (D10Rat29)
Rat AssemblyChrPosition (strand)Source
Rnor_6.01067,988,035 - 67,988,218NCBI
Rnor_5.01067,642,121 - 67,642,304UniSTS
RGSC_v3.41068,842,878 - 68,843,272RGD
RGSC_v3.41068,842,891 - 68,843,074UniSTS
RGSC_v3.11068,856,501 - 68,856,895RGD
Celera1064,569,293 - 64,569,476UniSTS
RH 2.0 Map10657.7RGD
SHRSP x BN Map1046.5699RGD
FHH x ACI Map1053.73RGD
Cytogenetic Map10q26UniSTS
Strain QTL Data
Symbol Name Trait
Eae18 Experimental allergic encephalomyelitis QTL 18 nervous system integrity trait   (VT:0010566)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease Rats display a reduced susceptibility to experimental allergic encephalomyelitis. 1302800
strain_other Total contamination of the DA genotype with ACI sequences is estimated to be 0.47%. 1302800

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-04-21 DA.ACI-(D10Rat2-D10Rat29)/Kini    DA.ACI-(D10Rat2-D10Rat29   Symbol updated 68687 APPROVED
2014-04-21 DA.ACI-(D10Rat2-D10Rat29)/Kini    DA.ACI-(D10Rat2-D10Rat29   Name updated 68913 APPROVED
2014-04-21 DA.ACI-(D10Rat2-D10Rat29)/Kini    DA.ACI-(D10Rat2-D10Rat29)/Kini    Name updated 68913 APPROVED
2014-04-21 DA.ACI-(D10Rat2-D10Rat29)/Kini    DA.ACI-(D10Rat2-D10Rat29   Name updated 68913 APPROVED
2014-04-21 DA.ACI-(D10Rat2-D10Rat29)/Kini    DA.ACI-(D10Rat2-D10Rat29)/Kini    Name updated 68913 APPROVED
2014-04-21 DA.ACI-(D10Rat2-D10Rat29)/Kini    DA.ACI-(D10Rat2-D10Rat29   Symbol updated 68687 APPROVED