Strain Report - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Strain Registration

Strain: LE-ROSA26 em1(CAG-Cas9)Ottc

Symbol: LE-ROSA26 em1(CAG-Cas9)Ottc
Strain: LE-ROSA26 em1(CAG-Cas9)Ottc
Substrain: Ottc
RGD ID: 13208224
Citation ID: RRID:RRRC_00833
Ontology ID: RS:0004519
Also Known As: LE-(ROSA)26 em1(CAG-Cas9)Ottc; LE-ROSA26tm1(LSL-Cas9)Ottc; LE-(ROSA)26 em1(CAG-Cas9)Ottc; LE-ROSA26 ^[em1(CAG-Cas9)Ottc]
Type: mutant
Available Source: Rat Resource and Research Center
Origination: Rat Resource and Research Center
Description: The CRISPR/Case9 knock-in rats have cre recombinase-dependent expression of Cas9 under the control of CAG promoter inserted to the rat ROSA26 locus. ROSA26 is a synonym for rat Thumpd3-as1 (RGD:6491660) and is used as an official symbol for rat strain nomenclature.
Last Known Status: Unknown






References

References - curated
# Reference Title Reference Citation
1. Personal Communication with OTTC Personal Communication with OTTC

Region


Additional Information


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-08-01 LE-ROSA26 em1(CAG-Cas9)Ottc    LE-(ROSA)26 em1(CAG-Cas9)Ottc    Symbol and/or name change 68913 APPROVED
2017-08-08 LE-(ROSA)26 em1(CAG-Cas9)Ottc    LE-Gt(Rosa)26 em1(CAG-Cas9)Ottc    Symbol updated 68687 APPROVED
2017-08-08 LE-(ROSA)26 em1(CAG-Cas9)Ottc    LE-Gt(Rosa)26 em1(CAG-Cas9)Ottc    Symbol updated 68687 APPROVED

Database Acc Id Source(s)
RRRC RRRC:00833 RGD