Strain Report - Rat Genome Database

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Strain: LEA/Tj

Symbol: LEA/Tj
Strain: LEA
Substrain: Tj
RGD ID: 1302729
Citation ID: RRID:RGD_1302729
Ontology ID: RS:0000444
Also Known As: NBRP Rat No: 0050
Type: inbred
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: Found in Long Evans strain at Kobe University; Inbreeding at Hokkaido University; Otsuka Pharmaceutical Co.; The University of Tokushima 1989
Inbred Generations: F47
Last Known Status: Live Animals; Cryopreserved Embryo
Research Usage Cancer





Experimental Data Annotations    Click to see Annotation Detail View

Rat Strain
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
LEA/TjRatLEA/Tj  IEA 7241799 RGD 

Vertebrate Trait
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
LEA/TjRatcoat/hair pigmentation trait  EXP 2317982 RGD 

References

References - curated
# Reference Title Reference Citation
1. Point mutation of aldehyde dehydrogenase-2 gene in mutant strains of Long-Evans rats. Nakajima M, etal., Alcohol Alcohol 1994;29 Suppl 1:39-43.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines
4. Genetic analysis of modifiers for the hooded phenotype in the rat. Torigoe D, etal., Jpn J Vet Res. 2010 Feb;57(4):175-84.
5. Low susceptibility to N-ethyl-N-nitrosourea-induced transplacental carcinogenesis in Long-Evans Cinnamon (LEC) rats. Tsuchigauchi T, etal., J Med Invest. 2009 Aug;56(3-4):93-8.

Region

Strain QTL Data
Symbol Name Trait
Coatc2 Coat color QTL 2 coat/hair pigmentation trait   (VT:0010463)    
Coatc3 Coat color QTL 3 coat/hair pigmentation trait   (VT:0010463)    
Coatc4 Coat color QTL 4 coat/hair pigmentation trait   (VT:0010463)    
Coatc5 Coat color QTL 5 coat/hair pigmentation trait   (VT:0010463)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_drgs_chems Neural tumors were seen after 60mg/kg ENU was given to pregnant rats. 2316901
strain_reproduction Good breeding performance. 1302502

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-06-12 LEA/Tj    LEA/Tj    Name updated 68913 APPROVED
2015-06-12 LEA/Tj    LEA/Tj    Name updated 68913 APPROVED
2012-05-08 LEA/Tj    LEA/Tj    Name updated 68913 APPROVED
2012-05-08 LEA/Tj    LEA/Tj    Name updated 68913 APPROVED