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Strain Registration

Strain: KND/Tky

Symbol: KND/Tky
Strain: KND
Substrain: Tky
Full Name: komeda non-diabetic rat
RGD ID: 1302697
Citation ID: RRID:RGD_1302697
Ontology ID: RS:0000418
Also Known As: MDC-02-77; NBRP Rat No: 0027
Type: inbred
Available Source: National BioResource Project for the Rat in Japan
Origination: National BioResource Project for the Rat in Japan
Description: Komeda diabetes-prone rat developed by Komeda from Long-Evans Tokushima Lean (LETL) rat at Tokyo Medical College in 1996. Komeda non Diabetic Rats were established simultaneusely as controls.
Coat Color: Agouti
Inbred Generations: F39
Last Known Status: Live Animals; Cryopreserved Embryo
Research Usage Diabetes Obesity





Disease Annotations     Click to see Annotation Detail View


References

References - curated
# Reference Title Reference Citation
1. Establishment of two substrains, diabetes-prone and non-diabetic, from Long-Evans Tokushima Lean (LETL) rats. Komeda K, etal., Endocr J. 1998 Dec;45(6):737-44. doi: 10.1507/endocrj.45.737.
2. Examination of OLETF-derived non-insulin-dependent diabetes mellitus QTL by construction of a series of congenic rats. Kose H, etal., Mamm Genome 2002 Oct;13(10):558-62.
3. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines
5. SNP and haplotype mapping for genetic analysis in the rat. Saar K, etal., Nat Genet. 2008 May;40(5):560-6.
6. Cblb is a major susceptibility gene for rat type 1 diabetes mellitus. Yokoi N, etal., Nat Genet 2002 Aug;31(4):391-4.

Region


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics Control strain of KDP rat. 625760
strain_reproduction brother x sister mating 625760

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-05-07 KND/Tky  komeda non-diabetic rat  KND/Tky  komeda non-diabetic rat  Name updated 68913 APPROVED