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Strain: F344.OLETF-(D5Mgh5-D5Mgh23)/Tj

Symbol: F344.OLETF-(D5Mgh5-D5Mgh23)/Tj
Strain: F344.OLETF-(D5Mgh5-D5Mgh23)
Substrain: Tj
RGD ID: 1302667
Citation ID: RRID:RGD_1302667
Ontology ID: RS:0000293
Previously known as: F.O-Nidd7/of; F344.OLETF-(D5Mgh5-D5Mgh23)/Tj
Type: congenic
Source: National BioResource Project for the Rat in Japan
Origin: Male OLETF was crossed with female F344. F1 were backcrossed to female F344 for 5 generations. Microsatellite-based genotyping was performed to select the best male that had the best OLETF donor genome. Once the region was fixed the resultant congenic strain was maintained by brother-sister mating.37.4 cM segment of the OLETF genome was transferred.
Inbred Generations: F10
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2543,726,656 - 109,897,936RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0544,404,276 - 114,014,945RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0549,028,773 - 117,961,491RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4545,499,364 - 115,361,927RGD_MAPPER_PIPELINERGSC3.4





Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Examination of OLETF-derived non-insulin-dependent diabetes mellitus QTL by construction of a series of congenic rats. Kose H, etal., Mamm Genome 2002 Oct;13(10):558-62.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D5Mgh5)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2543,726,656 - 43,726,832 (+)MAPPER
Rnor_6.0544,404,276 - 44,404,451NCBI
Rnor_5.0549,028,773 - 49,028,948UniSTS
RGSC_v3.4545,499,364 - 45,499,540RGD
RGSC_v3.4545,499,365 - 45,499,540UniSTS
RGSC_v3.1545,499,544 - 45,499,719RGD
Celera542,531,874 - 42,532,049UniSTS
RH 3.4 Map5230.1UniSTS
RH 3.4 Map5230.1RGD
RH 2.0 Map5264.8RGD
SHRSP x BN Map522.8299RGD
Cytogenetic Map5 RGD

Flank 2 / 1 (D5Mgh23)
Rat AssemblyChrPosition (strand)Source
mRatBN7.25109,897,808 - 109,897,936 (+)MAPPER
Rnor_6.05114,014,818 - 114,014,945NCBI
Rnor_5.05117,961,364 - 117,961,491UniSTS
RGSC_v3.45115,361,799 - 115,361,927RGD
RGSC_v3.45115,361,800 - 115,361,927UniSTS
RGSC_v3.15115,367,025 - 115,367,153RGD
Celera5108,513,674 - 108,513,801UniSTS
RH 3.4 Map5779.4UniSTS
RH 3.4 Map5779.4RGD
RH 2.0 Map5702.5RGD
Cytogenetic Map5q34.1UniSTS

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics hyperglycemia after glucose challenge in the OGTT assay 625760
strain_reproduction Good breeding performance 625760

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-01-19 F344.OLETF-(D5Mgh5-D5Mgh23)/Tj    F344.OLETF-(D5Mgh5-D5Mgh23)/Tj    Name updated 68913 APPROVED
2015-01-19 F344.OLETF-(D5Mgh5-D5Mgh23)/Tj    F344.OLETF-(D5Mgh5-D5Mgh23)/Tj    Name updated 68913 APPROVED