Strain Report - Rat Genome Database

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Strain: F344.OLETF-(D5Rat166-D5Rat90)/Tj

Symbol: F344.OLETF-(D5Rat166-D5Rat90)/Tj
Strain: F344.OLETF-(D5Rat166-D5Rat90)
Substrain: Tj
RGD ID: 1302647
Citation ID: RRID:RGD_1302647
Ontology ID: RS:0000478
Previously known as: F.O-Nidd6/of; F344.OLETF-(D5Rat166-D5Rat90)/Tj; F344-nidd6
Type: congenic
Source: Laboratory of Animal Breeding and Genetics, Kyoto University, Sakyoku, Kyoto, Japan
Origin: Male OLETF was crossed with female F344. F1 were backcrossed to female F344 for 5 generations. Microsatellite-based genotyping was performed to select the best male that had the best OLETF donor genome. Once the region was fixed the resultant congenic strain was maintained by brother-sister mating.37.4 cM segment of the OLETF genome was transferred.
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25130,881,210 - 132,691,399RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.05136,271,682 - 138,128,882RGD_MAPPER_PIPELINERnor6.0
Rnor_5.05140,063,670 - 141,938,308RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.45137,718,909 - 139,664,499RGD_MAPPER_PIPELINERGSC3.4

Experimental Data Annotations    Click to see Annotation Detail View

Rat Strain
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
F344.OLETF-(D5Rat166-D5Rat90)/Tj  IEA 7241799 RGD 

Vertebrate Trait
TermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
blood glucose amount  EXP 625760 RGD 


References - curated
# Reference Title Reference Citation
1. Examination of OLETF-derived non-insulin-dependent diabetes mellitus QTL by construction of a series of congenic rats. Kose H, etal., Mamm Genome 2002 Oct;13(10):558-62.
2. Strains registered by the National Bio Resource Project for the Rat in Japan Personal Communication with NBRP
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines


Position Markers

Flank 1 / 1 (D5Rat166)
Rat AssemblyChrPosition (strand)Source
mRatBN7.25130,881,210 - 130,881,381 (+)MAPPER
Rnor_6.05136,271,682 - 136,271,852NCBI
Rnor_5.05140,063,670 - 140,063,840UniSTS
RGSC_v3.45137,718,909 - 137,719,080RGD
RGSC_v3.45137,718,910 - 137,719,080UniSTS
RGSC_v3.15137,724,135 - 137,724,306RGD
Celera5129,400,570 - 129,400,738UniSTS
Cytogenetic Map5q36UniSTS

Flank 2 / 1 (D5Rat90)
Rat AssemblyChrPosition (strand)Source
mRatBN7.25132,691,196 - 132,691,399 (+)MAPPER
Rnor_6.05138,128,680 - 138,128,882NCBI
Rnor_5.05141,938,106 - 141,938,308UniSTS
RGSC_v3.45139,664,296 - 139,664,499RGD
RGSC_v3.45139,664,297 - 139,664,499UniSTS
RGSC_v3.15139,669,523 - 139,669,725RGD
Celera5131,218,061 - 131,218,263UniSTS
RH 3.4 Map5868.7RGD
RH 3.4 Map5868.7UniSTS
RH 2.0 Map5859.0RGD
SHRSP x BN Map570.6499RGD
FHH x ACI Map569.91RGD
Strain QTL Data
Symbol Name Trait
Niddm24 Non-insulin dependent diabetes mellitus QTL 24 blood glucose amount   (VT:0000188)    

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease Not different from F344 rat in any of the observed diabetic phenotypes. 625760