Strain Report - Rat Genome Database

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Strain: LEXF4/Stm

Symbol: LEXF4/Stm
Strain: LEXF4
Substrain: Stm
RGD ID: 1302604
Citation ID: RRID:RGD_1302604
Ontology ID: RS:0000545
Also known as: NBRP Rat No: 0111; MDC-02-61
Type: recombinant_inbred
Source: National BioResource Project for the Rat in Japan
Origin: This strain is derived from systematic breeding of the F2 generation between LE/Stm and F344/DuCrlj.
Last Known Status: Cryopreserved Embryo
Research Usage Diabetes Obesity; Cancer





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Mammalian Phenotype

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
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Clinical Measurement
heart rate
systolic blood pressure
body weight
body temperature
red blood cell count
blood hemoglobin level
white blood cell count
platelet count
hematocrit
mean corpuscular volume
plasma glucose level
plasma aspartate aminotransferase activity level
plasma alanine aminotransferase activity level
plasma alkaline phosphatase activity level
plasma total protein level
plasma albumin level
plasma phosphate level
plasma chloride level
plasma sodium level
plasma potassium level
heart wet weight
heart weight to body weight ratio
both kidneys wet weight
lung wet weight
urine potassium level
urine sodium level
brain weight to body weight ratio
both kidneys wet weight as percentage of body weight
liver weight as percentage of body weight
spleen weight to body weight ratio
brain wet weight
lung weight to body weight ratio
liver wet weight
both adrenal glands wet weight
spleen wet weight
both testes wet weight
activated partial thromboplastin time
prothrombin time
timed urine volume
mean corpuscular hemoglobin
mean corpuscular hemoglobin concentration
blood basophil count to total leukocyte count ratio
blood eosinophil count to total leukocyte count ratio
blood lymphocyte count to total leukocyte count ratio
blood monocyte count to total leukocyte count ratio
total plasma calcium level
urine chloride level
plasma creatinine level
plasma triglyceride level
plasma total cholesterol level
plasma urea nitrogen level
both adrenal glands weight to body weight ratio
plasma high density lipoprotein cholesterol level
plasma low density lipoprotein cholesterol level
both testes wet weight to body weight ratio
percentage of study population developing leukemia during a period of time
urine sodium excretion rate to body weight ratio
post-insult time to onset of leukemia
post-insult time to onset of T-cell lymphoma
percentage of study population developing T-cell lymphomas during a period of time
timed urine volume to body weight ratio
urine chloride excretion rate to body weight ratio
urine potassium excretion rate to body weight ratio
plasma total bilirubin level
blood segmented neutrophil count to total leukocyte count ratio
blood band neutrophil count to total leukocyte count ratio
non-specified leukocyte count to total leukocyte count ratio
plasma albumin to plasma total protein ratio

References


Region

Damaging Variants
Number of Damaging Variants
SampleRnor_6.0Rnor_5.0RGSC_v3.4
LEXF4/Stm (2020) 2492
LEXF4/Stm (2020)


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_drgs_chems Oral administration of propylnitrosourea (PNU) induced 95.2% leukemia and 57.1% T-lymphoma incidence in these rats. 619600
strain_reproduction Good breeding performance. 628402

Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-05-09 LEXF4/Stm    LEXF4/Stm    Name updated 68913 APPROVED
2012-05-09 LEXF4/Stm    LEXF4/Stm    Name updated 68913 APPROVED