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Strain Registration

Strain: F344.DA-(D20Arb2-D20Arb8)/Arb

Symbol: F344.DA-(D20Arb2-D20Arb8)/Arb
Strain: F344.DA-(D20Arb2-D20Arb8)
Substrain: Arb
RGD ID: 1299880
Citation ID: RRID:RGD_1299880
Ontology ID: RS:0000276
Also Known As: F344.DA(Cia1); F344.DA(D20Arb2-D20Arb8)/Arb; F344.DA-(D20Arb2-D20Arb8)/Arb
Type: congenic
Available Source: Not Available
Origination: The National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, Maryland
Description: Region of interest was introgressed from DA/BklArb into F344/Hsd by eight to ten genotype guided backcrosses followed by minimum five intercrosses.
Inbred Generations: 198
Last Known Status: Unknown
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2202,646,395 - 2,666,654RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0203,151,815 - 3,172,069RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0205,249,981 - 5,270,235RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4202,790,511 - 2,811,567RGD_MAPPER_PIPELINERGSC3.4





Disease Annotations     Click to see Annotation Detail View
arthritis  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype

References

References - curated
# Reference Title Reference Citation
1. Genetic regulation of T regulatory, CD4, and CD8 cell numbers by the arthritis severity loci Cia5a, Cia5d, and the MHC/Cia1 in the rat. Brenner M, etal., Mol Med. 2007 May-Jun;13(5-6):277-87.
2. Modulation of multiple experimental arthritis models by collagen-induced arthritis quantitative trait loci isolated in congenic rat lines: different effects of non-major histocompatibility complex quantitative trait loci in males and females. Remmers EF, etal., Arthritis Rheum 2002 Aug;46(8):2225-34.
3. RGD Strain RSO annotation pipeline RGD Automated Pipelines

Region

Position Markers

Flank 1 / 1 (D20Arb2)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2202,666,495 - 2,666,654 (+)MAPPER
mRatBN7.2202,646,395 - 2,646,556 (+)MAPPER
Rnor_6.0203,151,815 - 3,151,975NCBI
Rnor_6.0203,171,911 - 3,172,069NCBI
Rnor_5.0205,270,077 - 5,270,235UniSTS
Rnor_5.0205,249,981 - 5,250,141UniSTS
RGSC_v3.4202,790,512 - 2,790,672UniSTS
RGSC_v3.4202,811,408 - 2,811,567RGD
RGSC_v3.4202,790,511 - 2,790,672RGD
RGSC_v3.4202,811,409 - 2,811,567UniSTS
RGSC_v3.1202,790,738 - 2,790,899RGD
Celera2076,870 - 77,030UniSTS
Celera2096,911 - 97,069UniSTS
SHRSP x BN Map200.0RGD
SHRSP x BN Map200.0UniSTS
FHH x ACI Map200.16RGD

Flank 2 / 1 (D20Arb8)
Rat AssemblyChrPosition (strand)Source
Cytogenetic Map20 RGD

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease This strain demonstrates a complete resistance to collagen-induced arthritis. 629569
strain_phys_biochem have similar CD4 T cells as F344 1642451