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Strain Registration

Strain: PKD/Mhm

Symbol: PKD/Mhm
Strain: PKD
Substrain: Mhm
Full Name: PKD
RGD ID: 11535000
Citation ID: RRID:RGD_11535000
Ontology ID: RS:0004217
Alleles: Anks6PKD
Previously known as: PKD/Mhm(cy/+)
Type: inbred
Source: Medical Research Centre, Klinikum Mannheim, University of Heidelberg, Mannheim, Germany
Origin: The colony of inbred PKD/Mhm rats was established in the laboratory in Mannheim after 18 additional generations of inbreeding of the Han:SPRD (cy/+).The mutation was a C to T transition that replaces an arginine by a tryptophan at amino acid 823 in the protein sequence.
Inbred Generations: F18
Last Known Status: Unknown (as of 2016-11-29)





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References

References - curated
# Reference Title Reference Citation
1. Missense mutation in sterile alpha motif of novel protein SamCystin is associated with polycystic kidney disease in (cy/+) rat. Brown JH, etal., J Am Soc Nephrol. 2005 Dec;16(12):3517-26. Epub 2005 Oct 5.

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