Strain Report - Rat Genome Database

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Strain: F344-Zeb2em1Kyo

Symbol: F344-Zeb2em1Kyo
Strain: F344-Zeb2em1
Substrain: Kyo
RGD ID: 11040916
Citation ID: RRID:RGD_11040916
Ontology ID: RS:0004121
Also known as: F344-Zeb2em1Kyo; NBRP Rat No: 0753
Type: mutant
Source: National BioResource Project for the Rat in Japan
Origin: Zinc-finger nucleases (ZFNs) method taregting exon 5 of Zeb2 gene (AGCCAAAGCTTGCCTCCA and GACTACTGACTCAAG) was used; This strain has a 5-bp deletion (cagag) and a 2-bp insertion (tc) in exon7 of Nrf2 gene, resulting in a deletion of Glutamine(Q)541. Background strain: F344/Stm
Coat Color: Albino
Last Known Status: Cryopreserved Sperm
Research Usage Neurobiology; Development


References - curated
1. Personal Communication with NBRP
2. RGD Automated Pipelines


Position Markers

Flank 1 / 1 (Zeb2)
Rat AssemblyChrPosition (strand)Source
mRatBN7.2329,219,765 - 29,342,094 (-)NCBI
mRatBN7.2 Ensembl329,218,301 - 29,345,157 (-)Ensembl
Rnor_6.0329,857,289 - 29,985,932 (-)NCBI
Rnor_6.0 Ensembl329,862,473 - 29,996,865 (-)Ensembl
Rnor_5.0335,058,725 - 35,186,767 (-)NCBI
RGSC_v3.4325,513,009 - 25,654,964 (-)NCBI
RGSC_v3.1325,409,380 - 25,556,869 (-)NCBI
Celera327,525,557 - 27,647,939 (-)NCBI
Cytogenetic Map3q12NCBI

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_characteristics No abnormalities in gross appearance and behavior. 1302502
strain_reproduction sib mating between homozygous rats. Good breeding performance. 1302502