Strain Report - Rat Genome Database

Name: F344.ZUC-( Lepr fa ),OLETF-( D14Rat23-D14Rat12 )/Tj
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain Registration

General

Strain: F344.ZUC-(Lepr^fa),OLETF-(D14Rat23-D14Rat12)/Tj

Symbol:

F344.ZUC-(Lepr^fa),OLETF-(D14Rat23-D14Rat12)/Tj

Strain:

F344.ZUC-(Lepr^fa),OLETF-(D14Rat23-D14Rat12)

Substrain:

RGD ID:

10755350

Citation ID:

RRID:RGD_10755350

Ontology ID:

RS:0004089

Previously known as:

F344.ZUC-(Leprfa),OLETF-(D14Rat23-D14Rat12)/Tj; F.ZF-Lepr & Nidd2/of; f344-fa-nidd2

Type:

congenic

Source:

National BioResource Project for the Rat in Japan

Origin:

The F344.ZUC,OLETF double congenic was produced by crossing F344.ZUC-Lepr^fa with F344.OLETF-( D14Rat23-D14Rat12) and then selecting Lepr^fa -Niddm20 (fa/fa-Nidd2/of) homozygotes

Last Known Status:

Unknown

Research Usage

Diabetes Obesity

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	116,294,409 - 116,477,904	RGD_MAPPER_PIPELINE	mRatBN7.2
mRatBN7.2	14	1,217,606 - 39,153,750	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	14	2,227,825 - 61,783,215	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_6.0	5	120,503,475 - 120,682,281	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	14	2,222,207 - 61,886,417	RGD_MAPPER_PIPELINE	Rnor5.0
Rnor_5.0	5	124,380,327 - 124,556,585	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	14	1,764,386 - 41,707,592	RGD_MAPPER_PIPELINE	RGSC3.4
RGSC_v3.4	5	122,320,075 - 122,503,449	RGD_MAPPER_PIPELINE	RGSC3.4

Annotation Click to see Annotation Detail View

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

impaired glucose tolerance (IAGP)

increased body weight (IAGP)

increased food intake (IAGP)

insulin resistance (IAGP)

Phenotype Values via PhenoMiner Click to see Annotation Detail View

Options:

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Download data table

View expanded data table

Clinical Measurement

body weight

mesenteric fat pad weight

retroperitoneal fat pad weight

epididymal fat pad weight

serum triglyceride level

serum total cholesterol level

retroperitoneal fat pad weight to body weight ratio

mesenteric fat pad weight to body weight ratio

epididymal fat pad weight to body weight ratio

adipocyte basal free fatty acid secretion

References

References - curated

#	Reference Title	Reference Citation
1.	RGD Strain RSO annotation pipeline	RGD Automated Pipelines
2.	New animal models reveal that coenzyme Q2 (Coq2) and placenta-specific 8 (Plac8) are candidate genes for the onset of type 2 diabetes associated with obesity in rats.	Sasaki D, etal., Mamm Genome. 2015 Dec;26(11-12):619-29. doi: 10.1007/s00335-015-9597-4. Epub 2015 Aug 22.

Region

Position Markers

Flank 1 / 2 (D14Rat23)

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	1,217,606 - 1,217,776 (+)	MAPPER
Rnor_6.0	14	2,227,825 - 2,227,992	NCBI
Rnor_5.0	14	2,222,207 - 2,222,374	UniSTS
RGSC_v3.4	14	1,764,386 - 1,764,554	RGD
RGSC_v3.4	14	1,764,387 - 1,764,554	UniSTS
RGSC_v3.1	14	1,764,386 - 1,764,554	RGD
Celera	14	1,256,962 - 1,257,129	UniSTS
RH 2.0 Map	14	0.0	RGD
FHH x ACI Map	14	1.33	RGD

Flank 2 / 2 (D14Rat12)

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	14	39,153,581 - 39,153,750 (-)	MAPPER
Rnor_6.0	14	61,783,047 - 61,783,215	NCBI
Rnor_5.0	14	61,886,249 - 61,886,417	UniSTS
RGSC_v3.4	14	41,707,423 - 41,707,592	RGD
RGSC_v3.4	14	41,707,424 - 41,707,592	UniSTS
RGSC_v3.1	14	41,709,814 - 41,709,983	RGD
Celera	14	38,346,383 - 38,346,551	UniSTS
RH 2.0 Map	14	500.7	RGD
SHRSP x BN Map	14	27.1799	RGD

Flank 1 / 1 (Lepr)

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	116,294,409 - 116,477,904 (+)	NCBI
mRatBN7.2 Ensembl	5	116,289,823 - 116,475,908 (+)	Ensembl
UTH_Rnor_SHR_Utx	5	118,847,763 - 119,019,098 (+)	NCBI
UTH_Rnor_SHRSP_BbbUtx_1.0	5	120,573,106 - 120,744,441 (+)	NCBI
UTH_Rnor_WKY_Bbb_1.0	5	120,624,429 - 120,795,760 (+)	NCBI
Rnor_6.0	5	120,503,475 - 120,682,281 (+)	NCBI
Rnor_6.0 Ensembl	5	120,564,645 - 120,682,221 (+)	Ensembl
Rnor_5.0	5	124,380,327 - 124,525,200 (+)	NCBI
Rnor_5.0	5	124,555,678 - 124,556,585 (+)	NCBI
RGSC_v3.4	5	122,320,075 - 122,503,449	NCBI
Celera	5	114,817,255 - 114,982,861 (+)	NCBI
RH 3.4 Map	5		RGD
Cytogenetic Map	5	q33	NCBI

Additional Information

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-09-06	F344.ZUC-(Lepr^fa),OLETF-(D14Rat23-D14Rat12)/Tj		F344.ZUC-(Lepr^fa),OLETF-(D14Rat23-D14Rat12)/Tj		Name updated	68913	APPROVED
2016-09-06	F344.ZUC-(Lepr^fa),OLETF-(D14Rat23-D14Rat12)/Tj		F344.ZUC-(Lepr^fa),OLETF-(D14Rat23-D14Rat12)/Tj		Name updated	68913	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: F344.ZUC-(Leprfa),OLETF-(D14Rat23-D14Rat12)/Tj

Mammalian Phenotype

Related Phenotype Data for Term "F344.ZUC-(Leprfa),OLETF-(D14Rat23-D14Rat12)/Tj" (RS:0004089)

Strain: F344.ZUC-(Lepr^fa),OLETF-(D14Rat23-D14Rat12)/Tj