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Strain Registration

Strain: WN/N

Symbol: WN/N
Strain: WN
Substrain: N
Full Name: Inbred Wistar; W/N
RGD ID: 10045
Citation ID: RRID:RGD_10045
Ontology ID: RS:0001082
Previously known as: MDC-04-46
Type: inbred
Source: NIH Animal Genetic Resource
Origin: Heston in 1942 from Wistar stock of Nettleship, to National Institutes of Health in 1950 at F15.
Genetic Markers: c
Coat Color: Albino,
Inbred Generations: F105
Last Known Status: Unknown





Phenotype Values via Phenominer Click to see Annotation Detail View

Related Phenotype Data for Term "WN/N" (RS:0001082)

Rat Strains:
Clinical Measurements:
Experimental Conditions:
Measurement Methods:

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table


References

References - curated
# Reference Title Reference Citation
1. Inbred Strains Festing, MFW, Inbred Strains, The Laboratory Rat, 1979, Baker HK, Lindsey JR, Weisbroth SH, 55-72, Academic Press
2. Update to previous Strain Data Festing, MFW, Personal Communication Update, Feb-2000
3. NIH Rat Strain Data NIH Rat Strain Data
4. RGD Strain RSO annotation pipeline RGD Automated Pipelines
5. SNP and haplotype mapping for genetic analysis in the rat. Saar K, etal., Nat Genet. 2008 May;40(5):560-6.

Region

Damaging Variants
Number of Damaging Variants
SampleRnor_6.0Rnor_5.0RGSC_v3.4
WN/N (KNAW) 617
WN/N (KNAW) 647
WN/N (MCW) 1516
WN/N (2020) 2727
WN/N (2020)


Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease Anterior pituitary tumours nearly 100% in females over 18 months of age, pheochromocytomas orpreneoplastic nodules in adrenal medulla about 40% in males, granulocytic leukaemia 14% in animals over 18 months of age. Rarely show hyperplastic cortical nodules or adrenal cortical adenomas. High incidence of severe chronic nephritis. (Snell 1967). High 10-week body weight in males (19/23) (Tanase et al 1982). High relative heart weight in 10-week old males (19/23)(Tanase et al 1982). 1004
strain_life_disease Anterior pituitary tumours nearly 100% in females over 18 months of age, pheochromocytomas orpreneoplastic nodules in adrenal medulla about 40% in males, granulocytic leukaemia 14% in animals over 18 months of age. Rarely show hyperplastic cortical nodules or adrenal cortical adenomas. High incidence of severe chronic nephritis. (Snell 1967). High 10-week body weight in males (19/23) (Tanase et al 1982). High relative heart weight in 10-week old males (19/23)(Tanase et al 1982). 634612