From Sprague-Dawley stock of an unknown source to Hoechst, Frankfurt. To O. Haferkamp, University of Ulm, to ITRI-TNO Rijswijk, The Netherlands in 1972 (van Hooft 1990). Note that other sublines of "SD" rats (including SD/A, SD/Cpb, and SD/Waa) are known to differ among themselves, and from this strain (Bender et al 1984, Festing and Bender 1984).
Less sensitive to the induction of mammary tumours by DMBA than two samples of outbred Sprague-Dawley rats; mean life-span 743+/-22 days (van Zwieten et al 1984)
Less sensitive to the induction of mammary tumours by DMBA than two samples of outbred Sprague-Dawley rats; mean life-span 743+/-22 days (van Zwieten et al 1984)
This strain was screened for genetic polymorphisms for 100 genomic loci in 55 genes ; Polymorphisms observed in this study can be found in NCBI dbSNP under accession numbers ss12588106 - ss12588203.