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Strain: MHS/Gib

Symbol: MHS/Gib
Strain: MHS
Substrain: Gib
Full Name: Milan Hypertensive Strain
RGD ID: 10025
RRID: RGD_10025
Ontology ID: RS:0000578
Also known as: MDC-03-44
Type: inbred
Source: Department of Sciences and Biomedical Technologies, University of Milan, Milan, Italy
Origin: Outbred Wistar rats with brother x sister mating and selection for high systolic blood pressure
Last Known Status: Unknown

Disease Annotations     Click to see Annotation Detail View
hypertension  (IAGP)

Phenotype Values via PhenoMiner     Click to see Annotation Detail View
Options:  View chart  |  Download data table  |  View expanded data table



Strain QTL Data
Symbol Name Trait
Bp57 Blood pressure QTL 57 arterial blood pressure trait   (VT:2000000)    
Bp58 Blood pressure QTL 58 arterial blood pressure trait   (VT:2000000)    
Bp59 Blood pressure QTL 59 arterial blood pressure trait   (VT:2000000)    
Bp60 Blood pressure QTL 60 arterial blood pressure trait   (VT:2000000)    
Damaging Variants
Number of Damaging Variants
MHS/Gib (ICL) 671
MHS/Gib (KNAW) 772
MHS/Gib (RGD) 1066

Additional Information

RGD Curation Notes
Note Type Note Reference
strain_life_disease Have elevated blood pressure after 2 months of age 1357950
strain_phys_biochem This strain was screened for genetic polymorphisms for 100 genomic loci in 55 genes ; Polymorphisms observed in this study can be found in NCBI dbSNP under accession numbers ss12588106 - ss12588203. 737878
strain_phys_biochem Lower inhibition of calpain by calpastain is observed in erythrocytes and kidney cells. 1357950