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Strain: BBDR/Rhw

Symbol: BBDR/Rhw
Strain: BBDR
Substrain: Rhw
Ontology ID: RS:0000073
Type: inbred
Source: R. H. William Laboratory, University of Washington, Seattle, Washington
Origin: S. Bieg and coworkers (1998) generated a congenic line in which diabetes and lymphopenia are controlled solely by Iddm 1. This strain was generated by nine cycles of cross-intercross breeding of diabetes-prone DP with DR BB rats. Iddm 1 in the BioBreeding (BB) rat designates the genomic region on rat Chromosome (Chr) 4 that harbors the gene causing peripheral T cell lymphopenia (Lyp) and diabetes. The average age of onset of diabetes was 85 +/- 53 days of age after the first and 67 +/- 10 days of age after the 9th cycle.
Last Known Status: Unknown





References - curated
RGD Disease Portals

Region

Strain QTL Data

Additional Information

RGD Curation Notes
Nomenclature History
 
More on this Strain
Strain Nomenclature
Strain Registration

RGD Object Information
RGD ID: 10003
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2000-05-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.