RGD Reference Report - Prostaglandin F synthase. - Rat Genome Database

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Prostaglandin F synthase.

Authors: Watanabe, Kikuko 
Citation: Watanabe K, Prostaglandins Other Lipid Mediat. 2002 Aug;68-69:401-7.
RGD ID: 8552774
Pubmed: PMID:12432932   (View Abstract at PubMed)

Prostaglandin (PG) F2 is synthesized via three pathways from PGE2, PGD2, or PGH2 by PGE 9-ketoreductase, PGD 11-ketoreductase, or PGH 9-, 11-endoperoxide reductase, respectively. The enzymological and molecular biological properties of these enzymes have been reported in work over the last 30 years. Here, these three pathways of PGF synthesis by these enzymes are reviewed, and the physiological roles of the enzymes are discussed.



Molecular Pathway Annotations    Click to see Annotation Detail View

RGD Manual Annotations


  
Objects Annotated

Genes (Rattus norvegicus)
Akr1c3  (aldo-keto reductase family 1, member C3)
Cbr1  (carbonyl reductase 1)

Genes (Mus musculus)
Akr1c18  (aldo-keto reductase family 1, member C18)
Cbr1  (carbonyl reductase 1)

Genes (Homo sapiens)
AKR1C3  (aldo-keto reductase family 1 member C3)
CBR1  (carbonyl reductase 1)


Additional Information