RGD Reference Report - Acute phase proteins, C9, factor B, and lysozyme in recurrent oral ulceration and Behcet's syndrome. - Rat Genome Database

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Acute phase proteins, C9, factor B, and lysozyme in recurrent oral ulceration and Behcet's syndrome.

Authors: Lehner, T  Adinolfi, M 
Citation: Lehner T and Adinolfi M, J Clin Pathol. 1980 Mar;33(3):269-75.
RGD ID: 7411737
Pubmed: (View Article at PubMed) PMID:6900632

The concentrations and sequential changes of some acute phase proteins, factor B, and lysozyme have been assayed in recurrent oral ulceration and Behcet's syndrome. C9 was elevated in both groups of patients and was the sensitive index of disease activity; however, it failed to discriminate between the three types of recurrent oral ulcers and four types of Behcet's syndrome. The level of alpha 1 acid glycoprotein and lysozyme were significantly increased predominantly in the ocular type, whereas factor B was significantly increased especially in the neurological type of Behcet's syndrome. It is suggested that the changes in the concentrations of some plasma proteins may help our understanding of tissue involvement in Behcet's syndrome, as well as in the selection of therapeutic agents in this disease.

Annotation

Disease Annotations    
Behcet's disease  (IEP,ISO)

Objects Annotated

Genes (Rattus norvegicus)
Cfb  (complement factor B)

Genes (Mus musculus)
Cfb  (complement factor B)

Genes (Homo sapiens)
CFB  (complement factor B)


Additional Information