RGD Reference Report - Association of annexin V with prolactin in the rat anterior pituitary gland. - Rat Genome Database
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Association of annexin V with prolactin in the rat anterior pituitary gland.

Authors: Kawaminami, M  Tanaka, K  Asawa, T  Osugi, S  Kawauchi, H  Kurusu, S  Hashimoto, I 
Citation: Kawaminami M, etal., Biochem Biophys Res Commun. 1992 Jul 31;186(2):894-8.
RGD ID: 7241860
Pubmed: (View Article at PubMed) PMID:1386737

When pituitary extracts were subjected to non denaturing polyacrylamide gel electrophoresis, an unknown protein was found to associate with a proportion of the prolactin. This protein was dissociated from prolactin by sodium dodecyl sulfate. The protein was purified and sequenced. As the amino terminus was blocked, the amino acid sequences of three peptide fragments were determined. The obtained sequences of 41 amino acids were identical to partial sequences of a known protein, rat Annexin V. The molecular mass, 36 kDa, was also the same as the molecular weight of Annexin V. The existence of Annexin V mRNA in rat pituitary glands was also confirmed by polymerase chain reaction. These results show that Annexin V, a member of the calcium-dependent phospholipid binding proteins, is synthesized in the rat pituitary gland, and suggest its association with prolatin in the gland.


Gene Ontology Annotations    

Molecular Function

Objects Annotated

Genes (Rattus norvegicus)
Anxa5  (annexin A5)

Additional Information