RGD Reference Report - Genetic Selection for Voluntary Alcohol consumption in the Albino Rat - Rat Genome Database

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Genetic Selection for Voluntary Alcohol consumption in the Albino Rat

Authors: Research Laboratories of the State Alcohol Monopoly (Alko),   HELSINKI  FINLAND 
Citation: Science 159, 739-741 (1968)
RGD ID: 70283
Pubmed: PMID:17795073   (View Abstract at PubMed)

By outbreading Wistar rats and selecting for breeding animals that differ in their alcohol consumption, we have raised two genetically different lines. Marked differences between the sexes and the strains were evident by the eighth generation. Selection is reflected in the regression coefficient .754, which accounts for 65.9 percent of the variance. The heritabilities differ significantly in the two sexes, h2 for the males being .263, and for the females .371; this difference seems mainly ascribable to sex-linkage of some of the genetic factors controlling voluntary consumption of alcohol.



Phenotype Annotations    Click to see Annotation Detail View

Mammalian Phenotype

Object SymbolSpeciesTermQualifierEvidenceWithNotesSourceOriginal Reference(s)
AARatalcohol preference  IAGP  RGD 
ANARatlow alcohol preference  IAGP  RGD 
Objects Annotated

Strains
AA  (Alko, Alcohol)
ANA  (Alko, Non-Alcohol)


Additional Information