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Plasma exchange therapy for the treatment of Escherichia coli O-157 associated hemolytic uremic syndrome.

Authors: Nakatani, T  Tsuchida, K  Yoshimura, R  Sugimura, K  Takemoto, Y 
Citation: Nakatani T, etal., Int J Mol Med. 2002 Nov;10(5):585-8.
Pubmed: (View Article at PubMed) PMID:12373296

Plasma exchange (PE) therapy was administered to three patients with Escherichia coli O-157 associated hemolytic uremic syndrome (HUS) in early phase. Following several PE treatments, all cases completely recovered without any apparent complications. The usefulness of PE therapy in removing microbial fragments and inflammatory cytokines was evaluated. The peptidoglycan (PG) level, interleukin-1 receptor antagonist (IL-1Ra) were higher in HUS patients starting PE therapy than in patients who had received several sessions of PE therapy. PE therapy was an effective early phase treatment for Escherichia coli O-157 associated HUS.


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RGD Object Information
RGD ID: 6909171
Created: 2012-11-13
Species: All species
Last Modified: 2012-11-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.