RGD Reference Report - The cell biology of vision. - Rat Genome Database

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The cell biology of vision.

Authors: Sung, Ching-Hwa  Chuang, Jen-Zen 
Citation: Sung CH and Chuang JZ, J Cell Biol. 2010 Sep 20;190(6):953-63. doi: 10.1083/jcb.201006020.
RGD ID: 6903217
Pubmed: PMID:20855501   (View Abstract at PubMed)
PMCID: PMC3101587   (View Article at PubMed Central)
DOI: DOI:10.1083/jcb.201006020   (Journal Full-text)

Humans possess the remarkable ability to perceive color, shape, and motion, and to differentiate between light intensities varied by over nine orders of magnitude. Phototransduction--the process in which absorbed photons are converted into electrical responses--is the first stage of visual processing, and occurs in the outer segment, the light-sensing organelle of the photoreceptor cell. Studies of genes linked to human inherited blindness have been crucial to understanding the biogenesis of the outer segment and membrane-trafficking of photoreceptors.


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